Isotonicity


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Isotonicity

 

relative constancy of osmotic pressure in the fluid media and tissues of the body, a result of the maintenance at a given level of the concentrations of electrolytes, proteins, and other substances.

Isotonicity is one of the body’s most important physiological constants, which are ensured by mechanisms of self-regulation. Deviation of osmotic pressure from the normal physiological level (≈76–0.81 meganewtons per sq m, or 7.6–8.1 atmospheres) leads to the disruption of metabolic processes between the blood and the interstitial fluid.

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References in periodicals archive ?
The book will also include new chapters on Isotonicity, Intravenous Fluids, and Nutritional Calculations.
To ensure the validity of the DEA model specification, an isotonicity test (according to Golany and Roll (1989)) was conducted.
To ensure thorough homogenization, the homogenate was subjected to two round of freeze-thaw and centrifuged at 1,000 g for 10 min at 4[degrees]C, the suspension was collected and pellet was homogenized again, then supernatants from each centrifugation-step were pooled and equal volume of 2xPBS was added to restore isotonicity.