Jean Dausset

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Dausset, Jean

(zhäN dōsĕ`), 1916–2009, French immunologist. A physician specializing in blood diseases, he was the laboratory director of the National Blood Transfusion Center (1946–63) and a professor at the Univ. of Paris (1958–77) and the Collège de France. He identified a gene complex (human leucocyte A complex, or HLA) that accounted for different immunological reactions in humans to blood transfusions and to the introduction of foreign tissues. This was similar to the H-2 complex in mice identified by George SnellSnell, George Davis,
1903–96, American immunologist, b. Bradford, Mass., Ph.D. Harvard, 1930. He was associated with the Jackson Laboratory in Bar Harbor, Maine from 1935 to 1973.
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. The discovery revolutionized the understanding of the human immune system and aided enormously in the success of organ transplant surgery. Dausset, Snell, and Baruj BenacerrafBenacerraf, Baruj
, 1920–2011, American immunologist, b. Caracas, Venezuela, grad. Columbia (B.S., 1942), Medical College of Virginia (M.D., 1945). Raised in Paris, his Sephardic Jewish family fled the Nazis and came to the United States at the outset of World War II; he
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 shared the 1980 Nobel Prize in Physiology or Medicine for their discoveries concerning the relationship between genetics and the immune system. In 1984 Dausset established a research institute in Paris, which became (1993) the Foundation Jean Dausset–CEPH; he served as its president until 2003. The nonprofit institute coordinated the first international collaboration for the mapping of the human genome. Dausset also coauthored a number of books including Histocompatibility (1976) and Immunology (1980).
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References in periodicals archive ?
The discovery of the first HLA antigen is credited to French immunologist Jean Dausset (1916-2009).
Three papers appeared in 1958 by Jean Dausset, Jon van Rood and Rose Payne, respectively, which laid the foundation of what was later to become the HLA complex.
The test will be carried out centrally in the "Jean Dausset" Laboratory, a reference lab, part of the Paris Hospital Group.
Transplant pioneer Jean Dausset, MD, the French Nobel laureate who discovered the human leukocyte antigen (HLA) system that made human tissue typing for transplantation possible, died of natural causes June 6, 2009 in Mallorca, Spain.
Immunology - Understanding about how the immune system distinguishes between cells and foreign cells went through huge developments in 1958 thanks to the work of French medical researcher Jean Dausset. This made organ transplantation feasible.