Julius Axelrod
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Axelrod, Julius
Axelrod, Julius
Born May 30, 1912, in New York. American physiologist and pharmacologist. Member of the National Academy of Sciences of the USA (1971).
Axelrod received his B.S. from City College in New York in 1933, and he later received his Ph.D. He performed research at New York University from 1945 to 1949. He joined the staff of the National Heart Institute in Bethesda, Md., in 1949 and was appointed head of the pharmacology section of the National Institute of Mental Health in 1955.
Axelrod’s principal works deal with the metabolism of norepinephrine; he discovered the basic way in which norepinephrine is rendered inactive. He also studied the role of disrupted catecholamine metabolism in the pathogenesis of hypertonia and certain diseases of the nervous system.
Axelrod shared a Nobel Prize with B. Katz and U. von Euler in 1970.
WORKS
“Metabolism of Epinephrine and Other Sympathomimetic Amines.” Physiological Review, 1959, vol. 39.“Methylation Reactions in the Formation and Metabolism of Catecholamines and Other Biogenic Amines.” Pharmacological Reviews, 1966, vol. 18.