erg

(redirected from KCNH2)
Also found in: Dictionary, Thesaurus, Medical.

erg

(ûrg), unit of workwork,
in physics and mechanics, transfer of energy by a force acting to displace a body. Work is equal to the product of the force and the distance through which it produces movement.
..... Click the link for more information.
 or energyenergy,
in physics, the ability or capacity to do work or to produce change. Forms of energy include heat, light, sound, electricity, and chemical energy. Energy and work are measured in the same units—foot-pounds, joules, ergs, or some other, depending on the system of
..... Click the link for more information.
 in the cgs systemcgs system,
system of units of measurement based on the metric system and having the centimeter of length, the gram of mass, and the second of time as its fundamental units. Other cgs units are the dyne of force and the erg of work or energy.
..... Click the link for more information.
 of units, which is based on the metric systemmetric system,
system of weights and measures planned in France and adopted there in 1799; it has since been adopted by most of the technologically developed countries of the world.
..... Click the link for more information.
; it is the work done or energy expended by a force of 1 dyne acting through a distance of 1 centimeter. In terms of the joulejoule
, abbr. J, unit of work or energy in the mks system of units, which is based on the metric system; it is the work done or energy expended by a force of 1 newton acting through a distance of 1 meter. The joule is named for James P. Joule.
..... Click the link for more information.
, the unit of work or energy in the mks system, 1 erg equals 0.0000001 joule.

Erg

 

a unit of work or energy in the centimeter-gram-second system. The symbol is erg. One erg is equal to the work done by a force of 1 dyne when the point at which the force is applied is displaced 1 cm in the direction of the force. One erg equals 10–7 joule = 6.24 × 1011 electron volts.


Erg

 

a general name for sand masses in the deserts of North Africa. Ergs are usually confined to low-lying parts of the relief. The largest are the Grand Erg Occidental and the Grand Erg Oriental. The relief consists mainly of dunes, which rise to 200–300 m in height, stretching in the direction of the prevailing trade winds.

erg

[ərg]
(geography)
A large expanse of the earth's surface that is covered with sand, generally blown by wind into dune formations.
(physics)
A unit of energy or work in the centimeter-gram-second system of units, equal to the work done by a force of magnitude of 1 dyne when the point at which the force is applied is displaced 1 centimeter in the direction of the force. Also known as dyne centimeter (dyne-cm).

ERG

(medicine)

erg

A unit of energy in the CGS system. It is equal to .0000001 joule in the MKS system. See CGS system.
References in periodicals archive ?
R190Q channel subfamily KQT 1893delC member 1 (P631fs/33) LQT2 KCNH2 Potassium voltage-gated p.
A rare allelic variant of KCNH2 encoding an Arg1047Leu amino acid variant was found in 3 of 80 wild-type alleles (Table 3).
We also identified eight different single-nucleotide polymorphisms (SNPs) in KCNH2 and one SNP in KCNE2 among the patients and the wild-type controls (Table 3).
The 29 probands without mutations in KCNH2 were also screened for mutations in KCNQ1, KCNE1, and SCN5A, and several additional mutations were found (M.
We have developed a rapid screening method for detection of mutations in the KCNH2 and KCNE2 genes involved in congenital and acquired LQTS.
Thus, although it has not been examined in a controlled study, we find it likely that the combined use of SSCP and HD, as described here, is more efficient than SSCP alone for mutation screening in the KCNH2 and KCNE2 genes.
A general testing strategy for the molecular diagnosis of LQTS, based on initial mutation screening, would be the following: (a) electrocardiographic measuring of the proband; (b) SSCP-HD screening of KCNH2 and KCNQ1; and (c) sequencing of abnormal conformers.
We found 11 mutations in KCNH2 in 40 families with LQTS, and this number is to be expected from the distribution of LQTS-associated mutations in the published literature as compiled in the LQTSdbase (www.
In the early days of LQTS-genotyping, most KCNH2 mutations were found in the S4-S5-pore-S6 region, and the clinical phenotype was often (10, 25-27), but not always (17, 28), characterized by a dominant mode of inheritance and high penetrance caused by a pore-associated mutation affecting the whole tetrameric HERG ion channel in a dominant-negative way and thus making it possible for the mutation to be identified by linkage studies (10, 27).