Karyopyknosis


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Related to Karyopyknosis: pycnotic, caseous necrosis

Karyopyknosis

 

shrinkage of a cell nucleus; one of the stages of necrobiosis preceding karyorrhexis and karyolysis.

The karyopyknotic nucleus shrinks because of a loss of water.It stains more intensively with basic dyes than does the nucleus of a normally functioning cell, since the nucleic acid, which isresponsible for such staining, splits off from the nucleoproteins in the nucleus.

References in periodicals archive ?
2B) whereby its chromatin is distributed irregularly throughout the cytoplasm), karyopyknosis, nuclear vacuolization (Fig.
Karyorrhexis (double black arrows); Karyopyknosis in hepatocytes (green arrow); nuclear vacuolization (red arrow) and cytoplasmic degeneration (blue arrows).