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Related to Ketosis: ketoacidosis


Excess amounts of ketones in the body, especially associated with diabetes mellitus. Also known as ketoacidosis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



acetonemia, a disease of cows and sheep characterized by metabolic disturbance (carbohydrate-fat and protein). Affected are highly productive cows in the second to sixth week of lactation and multiparous sheep one to two weeks before lambing. The principal cause of ketosis is a carbohydrate deficiency connected with a dietary imbalance with respect to carbohydrate and protein. High milk yield, multiparity, and lack of exercise predispose to ketosis.

In sheep, ketosis develops predominantly when feeding is inadequate and the body is forced to meet its demand for nutritive substances at the expense of deposited fat.

The affected animals suffer digestive disturbances (decrease or perversion of appetite and weakening of the peristaltic and secretory activities of the digestive glands) and show an increase in the number of ketone bodies in the blood, urine, and milk. There is a decrease in milk productivity and a loss of weight. Nervous disturbances (agitation, depression) and a disruption of liver function are also observed. If untreated, the disease usually ends in the death of the animal. Treatment involves proper diet, intravenous injection of glucose, and the use of hormonal preparations. Ketosis can be prevented by properly feeding and keeping the animals.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The present study aimed at evaluating the early application of an oral Drench solution (immediately after calving and 24 h after) in relation to the metabolic profile and its potential for preventing subclinical ketosis in dairy cows from Southern Brazil.
The eventual appearance of SCK in cows on these areas might depend on the amount of butyric acid consumed and on the presence of other risk factors for ketosis (early lactation, high production, low dietary energy, etc.).
As with the cases presented in this report, despite having a tendency towards ketosis and an acute severe onset, patients with negative autoimmune markers, components of metabolic syndrome, and a family history for DM, have the characteristics of both groups.
Carina Norris, a dietician registered with the British Nutrition foundation, said, "Ketosis is not the normal way the body burns fat and we don't yet fully understand what it can do to you." In 2005, an Oxford University study found the diet could damage the heart.
By using the ketogenic diet, a person is put in a constant state of ketosis. The diet was popular until phenytoin came on the market and was seen as easier to use than maintaining the diet, she said.
Until the Atkins revolution ketosis was only usually seen in diabetics whose insulin control was disrupted.
Ketosis not only burns calories; it 'switches off' the appetite, signaling to the brain that there isn't much food around, so there's no point in making the person hungry.
The state, known to followers of the popular Atkins diet, is called ketosis. When blood-glucose concentrations get low, the liver converts a portion of fatty acids into acids called ketone bodies or ketones.
In the early 1920s, several researchers reported that this effect could be achieved without starving the patient, by inducing ketosis with a high fat, low carbohydrate diet in a specific ratio (2-4).
Taubes also told readers that a metabolic process called ketosis, often invoked to show the Atkins diet could be dangerous, was quite harmless, providing reassuring words from National Institutes of Health researcher Richard Veech that "ketosis is a normal physiologic state." Veech told me by e-mail that the quote was correct, but that Taubes "omitted to say that I strongly urged people to not use the Atkins diet without the supervision of a physician because of the likely elevation of blood cholesterol and lipid on a high fat diet." But you don't have an impact if you insist that a fad diet be supervised by a doctor.