kinetochore

(redirected from Kinetochores)
Also found in: Dictionary, Thesaurus, Medical.

kinetochore

[kə′ned·ə‚kȯr]
(cell and molecular biology)
Within the centromere, the granule upon which the spindle fibers attach.
References in periodicals archive ?
Essential roles of Drosophila inner centromere protein (Incenp) and Aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation.
These studies allowed us to gain deep knowledge on such important problems as: attachment of kinetochores to the spindle, kinetochore orientation and re-orientation during prometaphase I and metaphase I, in vivo orientation and segregation of the X chromosome, autosomal univalents, multiple chromosomal configurations (e.
Functional states of kinetochores revealed by laser microsurgery and fluorescent speckle microscopy.
Aurora Kinase is believed to function in signaling from unattached kinetochores to block progression to anaphase.
Key words: apoptosis, genotoxicity, kinetochores, micronuclei, ultrafine titanium dioxide.
The proteins reside in centrosomes, kinetochores, and nuclear membranes--structures involved in the dispersal of chromosomes in dividing cells--he and his coworkers report in the Sept.
Because the kinetochores are directly responsible for segregating chromatids during mitosis, a tempting hypothesis is that the asymmetric segregation is involved in nonrandom segregation of sister chromatids to daughter cells immediately after meiosis.
EB1 targets to kinetochores with attached, polymerizing microtubules.
Among the missing elements were kinetochores, the complexes of protein at the chromosomes' centromeres.
The binding of kinetochores to microtubules likely involves cooperative interactions between different copies of the kinetochore components.