aspartic acid

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aspartic acid

(əspär`tĭk), organic compound, one of the 20 amino acidsamino acid
, any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.
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 commonly found in animal proteins. Only the l-stereoisomer participates in the biosynthesis of proteins. Its acidic side chain adds a negative charge and hence a greater degree of water-solubility to proteins in neutral solution and has been shown to be near the active sites of some enzymes (see pepsinpepsin,
enzyme produced in the mucosal lining of the stomach that acts to degrade protein. Pepsin is one of three principal protein-degrading, or proteolytic, enzymes in the digestive system, the other two being chymotrypsin and trypsin.
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). Aspartic acid is not essential to the human diet. It was discovered in protein in 1868.

aspartic acid

[ə′spärd·ik ′as·əd]
(biochemistry)
C4H7NO4 A nonessential, crystalline dicarboxylic amino acid found in plants and animals, especially in molasses from young sugarcane and sugarbeet.
References in periodicals archive ?
Following condensation with L-aspartic acid dimethyl ester, regardless of whether 7-L-aspartic acid dimethyl ester was introduced alone or simultaneously with 4 ',7-di-Laspartic acid dimethyl ester, the hypoglycemic activity of the compounds was significantly decreased.
Seven percent of our strains utilized acetic acid, alaninamide, and L-aspartic acid; 27-33% showed a weak positive reaction to acetic acid, alaninamide, D-alanine, and L-alanine; and 7-13% were weakly positive to L-aspartic acid and hydroxy L-proline.
[11] Krebs, H.A., 1950, "Manometric determination of L-aspartic acid and L-asparagine," Cholesterol Metabolism, 47, 605-614.
added (including Eagle's MEM) SALTS (added in order) Grams Millimoles per liter Ca[Cl.sub.2] 3.647 17.6 KCl 1.358 11.78 Mg[Cl.sub.2] x 6[H.sub.2]O 8.714 21.45 Mg[SO.sub.4] x 7[H.sub.2]O 6.316 12.91 NaCl 48.520 473.25 NaH[CO.sub.3] 2.000 11.90 Hepes Buffer 4.766 10.00 Glucose 1.000 5.57 Glutamine 0.292 1.00 AMINO ACIDS Milligrams in 2 liters L-Alanine 1.8 L-Asparagine 3.0 L-Aspartic acid 2.7 L-Glutamic acid 2.9 L-Serine 2.1 Proline 2.3 Glycine 1.0 ml from stock (0.188 g/25 ml) for 0.05 ml ANTIBIOTICS Micrograms per milliliter Penicillin 200 Ampicillin 25 Streptomycin 200 Penicillin 200 SERUM % FBS (heat inactivated) 10
Electrosynthesized molecularly imprinted polypyrrole films for enantioselective recognition of L-aspartic acid. Electrochim.
The mixture was incubated for 16 h, and the reaction was terminated by the addition of L-glutamic acid and L-aspartic acid, 50 mmol/L each in the final solution, which was left to react for an additional 2 h.