asparaginase

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Related to L-asparaginase: methotrexate, cyclophosphamide, etoposide, vincristine

asparaginase

[‚as·pə′raj·ə‚nās]
(biochemistry)
An enzyme that catalyzes the hydrolysis of asparagine to asparaginic acid and ammonia.
References in periodicals archive ?
This extracellular activity is easier to Purify than the intracellular L-asparaginase Produced by bacteria and, whereas this can decrease The overall costs of production, it may also decrease Immunological reactions, once fungi are eukaryotes And their enzymes are expected to be more similar to Mammal proteins than prokaryote proteins.
coli L-asparaginase II, a periplasmic enzyme with high affinity for L-asparagine, has been applied clinically for treatment of acute lymphoblastic leukemia (30).
Keywords: Submerge fermentation, L-asparaginase, enzyme activity, optimum condition.
5,11,28) The use of L-asparaginase has been reported infrequently in treatment of avian neoplasia.
gulbargensis to produce L-asparaginase in a semi-continuous mode.
We know L-asparaginase is very important to treat patients with ALL, and we also know the toxicities related to this drug.
1974, "Amino acid sequence of L-asparaginase from Escherichia coli," J.
L-asparaginase, which is used in the treatment of leukaemia, can cause coagulopathy due to a decrease in antithrombin III and fibrinogen.