Carnitine

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Related to L-carnitine: taurine, acetyl l-carnitine, L-arginine

carnitine

[′kär·nə‚tēn]
(biochemistry)
C7H15NO3α-Amino-β-hydroxybutyric acid trimethylbetaine; a constituent of striated muscle and liver, identical with vitamin B T.

Carnitine

 

betaine-γ-amino-β-oxybutyric acid, (CH3)3NCH2CH(OH)CH2CO2, a crystalline compound with basic properties; dissolves readily in water and alcohol. Its molecular mass is 161.21, and its melting point, 195°-197°C (with decomposition).

Carnitine is primarily found in animal muscle, from which it was first extracted by V. S. Gulevich (1905); it is also found in bacteria and plants. It takes part in fatty exchange within an organism by acting as a carrier of fatty acid radicals through the membranes of the mitochondria. These membranes are impermeable to activated fatty acids (compounds with coenzyme A). With the aid of carnitine, therefore, fatty acids enter the scope of activity of the oxidizing enzymes localized within the mitochondria. Carnitine apparently also participates in the reverse transport of fatty acids. It is an essential dietary constituent and a growth factor in certain insects; therefore it is considered to be a vitamin (vitamin BT).

References in periodicals archive ?
The male breast meat in lines R and Y showed significantly higher L-carnitine content than did female breast meat, while there was no significant difference in L-carnitine content between genders in thigh meat.
L-carnitine is derived from lysine and methionine (amino acids) and is a foodstuff being found in meat and dairy products [17].
In one study, 160 male and female heart attack survivors between 39 and 86 years old received either (4) grams/day of L-carnitine or a placebo for (12) months.
Hazen's group also found that blood levels of TMAO and L-carnitine could predict heart disease risk, which they learned by collecting blood samples from 2,595 patients and tracking their health for three years.
Finally, while the present L-carnitine findings await further understanding and follow-up, there certainly does seem to be no compelling reason to start taking L-carnitine supplements.
Scientific evidence has shown that L-carnitine can optimize performance by positively affecting [VO.
Supplementation with L-carnitine also slows bone loss.
L-carnitine is an amino acid that transports fats into cells.
The ASA rulings follow a complaint by consumer activist Dr Harris Steinman against a commercial claiming the gel allowed users to 'say goodbye to cellulite', and that one of the ingredients, L-carnitine, was 'your skin's own fat burner'.
Nivea body's Good-Bye Cellulite Gel-Cream is specially formulated with L-Carnitine to help visibly reduce the appearance of cellulite.
Key words: cyclist, dietary carnitine, endurance-trained, L-carnitine, plasma carnitine, urinary carnitine excretion.