LAK cell | Article about LAK cell by The Free Dictionary
lymphokine-activated killer cell (redirected from LAK cell)
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lymphokine-activated killer cell[¦lim·fə‚kīn ¦ak·tə‚vād·əd ′kil·ər ‚sel]
A cytotoxic cell that is able to lyse certain cell lines resistant to natural killer cells.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
Although several clinical trials by intratumoral injection of LAK cells
combined with IL-2 for the glioblastoma patients have been carried out, most of their therapeutic effects have not shown a significant survival benefit [ 50-70].
Rosenberg first used LAK cells
and IL-2 in humans in 1984 in patients with advanced cancer.
When they combined TIL with only 10 to 20 percent of the interleukin-2 needed with LAK cells
and an immune system suppressor to fight off the body's attempt to get rid of the foreign cells, the researchers say they were able to "cure" mice with induced cancer.