LD50


Also found in: Dictionary, Thesaurus, Medical, Legal, Acronyms.
Related to LD50: LC50

LD50

(pharmacology)
Mentioned in ?
References in periodicals archive ?
Collected venom was freeze dried (lyophilized) using (Thermofreeze dryer PL-6000), and then stored at 2C to 7C in a light resistant container till LD50 calculation and envenomation.
the appearance of the drug manifestations after 15 to 30 minutes demonstrated by attacking and biting and injuring other animals; after this, they immediately were taken out of their cage and were placed in a separate cage and this time they turned out to bite and hurt themselves; of course this occurred in the communities with high doses from 50% LD50 to the full LD50.
The animals of group II underwent the effect of pesticide in dose 1/20 LD50 (7.
Percentage of dead individuals was registered for each dose until the day 14, settling down therefore the LD50 by kg of dry soil.
In vivo LD50 data in mice demonstrated tolerance of several of Upstream's anti-protozoan compounds at 5mg/kg and some were tolerated at even higher concentrations.
However, previous toxicological study has demonstrated that melamine is generally considered as a low toxicity to mammals [3], with a large oral LD50 of 3161 mg/kg in rats, and 90% of ingested melamine could be excreted by kidneys within 24 h.
Results obtained from dose response series or time response series after 24 hours were subjected to Probit Analysis (Lichfield and Wilcoxon, 1949) to determine LD50 and LT50.
The LD50 is usually determined by examining 50% survival studies, most of the genotypes produce viable seeds at 50% survival rate that was considered optimum dose; conversely some genotypes were unable to produce fertile seeds or did not fruit at this survival rate.
LD50 was determined by taking a dose of medication for induction of diabetes, along with drinking water for 98 days, daily fructose solvent cc 140 (10%) were used.