heparin

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Related to LMWH: Fondaparinux

heparin

(hĕp`ərĭn), anticoagulantanticoagulant
, any of several substances that inhibit blood clot formation (see blood clotting). Some anticoagulants, such as the coumarin derivatives bishydroxycoumarin (Dicumarol) and warfarin (Coumadin) inhibit synthesis of prothrombin, a clot-forming substance, and other
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 produced by cells in many animals. A polysaccharide, heparin is found in the human body and occurs in greatest concentration in the tissues surrounding the capillaries of the lungs and the liver. The substance, extracted from animal tissues, is used clinically to delay blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
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heparin

[′hep·ə·rən]
(biochemistry)
An acid mucopolysaccharide acting as an antithrombin, antithromboplastin, and antiplatelet factor to prolong the clotting time of whole blood; occurs in a variety of tissues, most abundantly in liver.
References in periodicals archive ?
Intermittent pneumatic compression device, UF, and LMWH are effective methods of DVT prophylaxis.
LMWHs can be used interchangeably, in accordance with local protocols [19].
All selected studies indicated subcutaneous injection of LMWH is related to adverse effects, such as bruising, pain, induration, and hematoma formation.
* LMWH prophylaxis should be continued until the patient is fully mobile.
demonstrated that LMWH significantly blocked coadhesion between connective tissue growth factor/CCN family 2 (CCN2) and low-density lipoprotein receptor-related protein 6 (LRP6) and enhanced chemotherapeutic effect of oxaliplatin on HCC [50].
Low-molecular-weight heparin (LMWH) has been increasingly used to treat thromboembolic disease in children as it has been shown to be as safe and effective as unfractionated heparin [1].
During follow-up the patient remained asymptomatic and neoadjuvant chemotherapy was begun and operated for ovarian cancer 5 months later, under LMWH (Enoxaparin) 8.000 once a day.
Due to the recent history of LMWH treatment, protamine sulfate was also administered but with no results.
Low Molecular Weight Heparin (LMWH): Low Molecular Weight Heparins are coagulation inhibiting glycosaminoglycans.
The patient was kept on therapeutic dose of LMWH because therapeutic INR range could not be achieved despite high doses of warfarin (15 mg of warfarin per day).
LMWH can suppress factor Xa by combining with ATIII to depress the activation of thrombin and formation of thrombosis so that it can be used for regular anticoagulation [50].