histiocytosis

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histiocytosis

[‚his·tē·ō‚sī′tō·səs]
(medicine)
Abnormal proliferation of histiocytes, especially in hematopoietic tissues.
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References in periodicals archive ?
Systemic Langerhans cell histiocytosis with bilateral temporal bone involvement in an adult.
Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical workup, and treatment for patients till the age of18 years.
Van Gool, "Paediatric neuroradiological aspects of Langerhans cell histiocytosis," Neuroradiology, vol.
The chest CT findings were identical to the expected radiological features for pulmonary Langerhans cell histiocytosis [20].
Langerhans cell histiocytosis (LCH) is a rare inflammatory myeloid neoplasia occurring in both children and adults [1].
Emile et al., "Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation," Blood, vol.
Langerhans cell histiocytosis (LCH) is a rare disorder of the reticuloendothelial system with unknown etiology [12].
He is slowly recovering from pulmonary Langerhans cell histiocytosis, a form of cancer that causes cysts on the lungs.
(Currently, CD1a antibodies are available, but their use is limited to resistant Langerhans cell histiocytosis. (14,15)) Although much remains to be understood, the importance of interactions between an "alarmed" skin barrier leading to ILC2 activation and expansion within the skin--with expression of IL-13 and subsequent recruitment of activated T cells, leading to further IL-13/IL-4 expression-is emerging as a driving pathway in this disease.
(Currently, CD1a antibodies are available, but their use is limited to resistant Langerhans cell histiocytosis. (14,15) ) Although much remains to be understood, the importance of interactions between an "alarmed" skin barrier leading to ILC2 activation and expansion within the skin--with expression of IL-13 and subsequent recruitment of activated T cells, leading to further IL-13/IL-4 expression--is emerging as a driving pathway in this disease.

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