Leishmania


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Leishmania

[lēsh′man·ē·ə]
(invertebrate zoology)
A genus of flagellated protozoan parasites that are the etiologic agents of several diseases of humans, such as leishmaniasis.

Leishmania

 

a genus of protozoans of the class Mastigophora.

Several species of Leishmania are known, although most are parasites of reptiles. Three species (L. donovani, L. tropica, and L. brasiliensis) are intracellular parasites of man and some animals, such as dogs. The organisms are transmitted by bloodsucking insects (sandflies of the genus Phlebotomus). L. donovani and L. tropica are found in the tropics and subtropics of Eurasia; L. brasiliensis is found in Central and South America. L. donovani is the causative agent of visceral leishmaniasis, or kala-azar, a serious disease of man that is widespread in India, China, and Sumatra; in the USSR, it appears from time to time in Middle Asia.

Leishmanias localize in the cells of the reticuloendothelial system, including those of the lymph nodes. The body is pear-shaped, 2–4 µm long, and has one nucleus and a kinetoplast. In the body of the animal host, the organism develops into a flagellate leptornonad form.

L. tropica, the causative agent of cutaneous leishmaniasis (Penjdeh sore), is morphologically similar to L. donovani. In the USSR, it is found in Middle Asia and Transcaucasia.

IU. I. POLIANSKII

References in periodicals archive ?
According to the World Health Organization, the incrimination of a particular mammal as a Leishmania reservoir must depend on an accumulation of evidence (9).
According to information coming in from district South Waziristan, Leishmania has reached epidemic proportions and DHQ hasn't that much expertise to tackle the epidemic properly, while locals speaking to the Daily Express urged the security forces to take the issue in hand and take responsibility for eradicating the disease.
Uygun tedavinin planlanmasi icin etken olan Leishmania turunun hizli bir sekilde belirlenmesi oldukca onemlidir.
Some studies have demonstrated a correlation between renal impairment and Leishmania nucleic acid in urine, (16,21) while others reported detection of L.
Antigens of leishmania homolog of receptors for activated c-kinase (LACK) and Thiol-Specific-Antioxidant (TSA) have been reported as the preventive vaccine candidates (9,10).
According to the health officials, leishmania is caused by the bite of a kind of mosquito known as sand fly, found in hilly areas, which usually breeds in fresh water.
Leishmania parasite cultivation in routine diagnostic and research laboratories is facing a major problem of microbial contamination despite strict adherence on aseptic microbiological practices.
Leishmania (L.) infantum chagasi is implicated as the aetiological agent that is transmitted by Lutzomyia longipalpis sand flies that bite the vertebrate hosts [1].
The article titled "Dendritic Cells and Leishmania Infection: Adding Layers of Complexity to a Complex Disease" [1] was found to contain material from published work without citation, as follows: