Leishmania


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Leishmania

[lēsh′man·ē·ə]
(invertebrate zoology)
A genus of flagellated protozoan parasites that are the etiologic agents of several diseases of humans, such as leishmaniasis.

Leishmania

 

a genus of protozoans of the class Mastigophora.

Several species of Leishmania are known, although most are parasites of reptiles. Three species (L. donovani, L. tropica, and L. brasiliensis) are intracellular parasites of man and some animals, such as dogs. The organisms are transmitted by bloodsucking insects (sandflies of the genus Phlebotomus). L. donovani and L. tropica are found in the tropics and subtropics of Eurasia; L. brasiliensis is found in Central and South America. L. donovani is the causative agent of visceral leishmaniasis, or kala-azar, a serious disease of man that is widespread in India, China, and Sumatra; in the USSR, it appears from time to time in Middle Asia.

Leishmanias localize in the cells of the reticuloendothelial system, including those of the lymph nodes. The body is pear-shaped, 2–4 µm long, and has one nucleus and a kinetoplast. In the body of the animal host, the organism develops into a flagellate leptornonad form.

L. tropica, the causative agent of cutaneous leishmaniasis (Penjdeh sore), is morphologically similar to L. donovani. In the USSR, it is found in Middle Asia and Transcaucasia.

IU. I. POLIANSKII

References in periodicals archive ?
A female victim of the disease, daughter of Arab Shah, resident of Kam-Shelman, said that 2 months ago, she suffered from leishmania and had been visiting the hospital since then.
The size and restriction fragment length polymorphism banding pattern of the ITS1 amplicon was distinct from all previously sampled human Leishmania species.
La deteccion inmunohistoquimica de amastigotes de Leishmania sp en secciones de tejidos caninos fijados en formol y embebidas en parafina, son rutinariamente utilizados en los laboratorios (3) .
The Chi-square and Fisher's exact were used to evaluate significant risk factors associated with seroprevalence of Leishmania spp.
Based on clinical and histological picture of chronic ulcerated dermatitis associated with leishmanias, the diagnosis of disseminated cutaneous leishmaniasis was established, the treatment with meglumine antimoniate 20mg/kg/day was started, and administered for 30 days.
We describe here sensitive and specific Leishmania genus (LEIS) and visceral Leishmania (LVL) TaqMan PCR assays (ThermoFisher Scientific, Waltham, MA) which clearly show promise as an aid in diagnosis.
Leishmania parasite promastigotes were cultured with Roswell Park Memorial Institute (RPMI) 1640 medium (Sigma, St.
In a study conducted by Mirzae et al, (14) approximately one-third of the rodents captured from the deserts in Fars Province and Turkmen Sahra tested positive for Leishmania, with L.
En el caso de la leishmaniosis visceral canina, se han empleado con exito vacunas con fracciones del parasito, entre ellas la Leishmune[R], que consiste en una preparacion enriquecida de glicoproteina de promastigotos de Leishmania donovani, llamada ligando de fucosa-manosa (FML, por su sigla en ingles) que es formulada con saponina de Quillaja saponania, como adyuvante.
In 1-10% of patients, leishmania disseminates from the skin to the nasooropharyngeal mucosa, resulting in mucosal leishmaniasis (ML) and destruction of nasal and pharyngeal structures.
Therefore, evaluation of the effects of bisphosphonate compounds on Leishmania parasites is warranted.
The number of leishmania lesions was charted, along with a description of their appearance, induration, size in millimeters and their location.