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(invertebrate zoology)
A genus of flagellated protozoan parasites that are the etiologic agents of several diseases of humans, such as leishmaniasis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a genus of protozoans of the class Mastigophora.

Several species of Leishmania are known, although most are parasites of reptiles. Three species (L. donovani, L. tropica, and L. brasiliensis) are intracellular parasites of man and some animals, such as dogs. The organisms are transmitted by bloodsucking insects (sandflies of the genus Phlebotomus). L. donovani and L. tropica are found in the tropics and subtropics of Eurasia; L. brasiliensis is found in Central and South America. L. donovani is the causative agent of visceral leishmaniasis, or kala-azar, a serious disease of man that is widespread in India, China, and Sumatra; in the USSR, it appears from time to time in Middle Asia.

Leishmanias localize in the cells of the reticuloendothelial system, including those of the lymph nodes. The body is pear-shaped, 2–4 µm long, and has one nucleus and a kinetoplast. In the body of the animal host, the organism develops into a flagellate leptornonad form.

L. tropica, the causative agent of cutaneous leishmaniasis (Penjdeh sore), is morphologically similar to L. donovani. In the USSR, it is found in Middle Asia and Transcaucasia.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Antileishmanial antibody profile in dogs naturally infected with Leishmania chagasi. Vet Immunol Immunopathol 2005; 106:151-151.
Establishment and Characterization of a New Continuous Cell Line from Lutzomyia longipalpis (Diptera: Psychodidae) and its Susceptibility to Infections with Arboviruses and Leishmania chagasi. Mem.
(2005) reportaron la actividad in vitro de alcaloides isoquinolinicos contra promastigotes de Leishmania chagasi, los extractos con alcaloides fueron obtenidos de Annona coriacea, Annona crassiflora, entre otras plantas.
La segunda y mas reciente, una prueba inmunoenzimatica basada en un antigeno recombinante compuesto por una secuencia repetitiva de 39 aminoacidos de Leishmania chagasi (rK39), tiene un formato mas sencillo de tira reactiva y ofrece resultados cualitativos (positivo o negativo) en solo 20 minutos.
The aim of the present work was to evaluate Leishmania chagasi interaction with a cell line (Lulo) previously established and derived from Lutzomyia longipalpis embryonic tissues, bearing different temperatures and C[O.sub.2] concentrations in mind and morphometric changes of the cells.
A la doctora Martha Ayala del laboratorio de parasitologia del Instituto Nacional de Salud, por la colaboracion y el apoyo con la cepa de Leishmania chagasi.
Keywords: Leishmaniasis; Chagas disease; Isoquinoline alkaloids; Trypanosoma cruzi; Leishmania chagasi
Serum samples were submitted to indirect immunofluorescent assay (IFA) with antigens of Leishmania chagasi, adopting 40 as the cutoff titer for positivity.
Prata et al., "Mixed inflammatory/regulatory cytokine profile marked by simultaneous raise of interferon-y and interleukin-10 and low frequency of tumour necrosis factor-[alpha]+ monocytes are hallmarks of active human visceral Leishmaniasis due to Leishmania chagasi infection," Clinical & Experimental Immunology, vol.

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