Leishmania

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Leishmania

[lēsh′man·ē·ə]
(invertebrate zoology)
A genus of flagellated protozoan parasites that are the etiologic agents of several diseases of humans, such as leishmaniasis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Leishmania

 

a genus of protozoans of the class Mastigophora.

Several species of Leishmania are known, although most are parasites of reptiles. Three species (L. donovani, L. tropica, and L. brasiliensis) are intracellular parasites of man and some animals, such as dogs. The organisms are transmitted by bloodsucking insects (sandflies of the genus Phlebotomus). L. donovani and L. tropica are found in the tropics and subtropics of Eurasia; L. brasiliensis is found in Central and South America. L. donovani is the causative agent of visceral leishmaniasis, or kala-azar, a serious disease of man that is widespread in India, China, and Sumatra; in the USSR, it appears from time to time in Middle Asia.

Leishmanias localize in the cells of the reticuloendothelial system, including those of the lymph nodes. The body is pear-shaped, 2–4 µm long, and has one nucleus and a kinetoplast. In the body of the animal host, the organism develops into a flagellate leptornonad form.

L. tropica, the causative agent of cutaneous leishmaniasis (Penjdeh sore), is morphologically similar to L. donovani. In the USSR, it is found in Middle Asia and Transcaucasia.

IU. I. POLIANSKII

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
(5.) Sarah Kerr, Chad McHugh, Robert Merkelz, Short Report: A Focus of Leishmania mexicana Near Tucson, Arizona, 1999
Uptake and killing of Leishmania mexicana amazonensis amastigotes by human skin fibroblasts.
Short report: a disseminated infection of Leishmania mexicana in an eastern woodrat, Neotoma floridana, collected in Texas.
Structure-function analysis of antimicrotubule dinitroanilines against promastigotes of the parasitic protozoan Leishmania mexicana. Antimicrob Agent Chemother 1993; 37(9): 1909-13.
El control positivo para Leishmania provino de un raton infectado con Leishmania mexicana, y el control positivo de Wolbachia se obtuvo de Culex quinquefasciatus el cual es conocido por ser portador de Wolbachia (Glaser & Meola 2010).
There are no vaccines at this time but there has been some study on a vaccine to Leishmania mexicana.
Sin embargo, las hidrazonas 2 y 4 fueron evaluadas in vitro contra cultivos de promastigote de Leishmania mexicana, encontrandose un CMI de 10[micron]M.
(1997) Identification of a transcription factor like protein at the TOR locus in Leishmania mexicana amazonensis.
The susceptibility of wild caught sand flies to infection by a subspecies of Leishmania mexicana isolated from Proechimys iheringi denigratus (Rodentia, Echimyidae).