Leishmania

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Leishmania

[lēsh′man·ē·ə]
(invertebrate zoology)
A genus of flagellated protozoan parasites that are the etiologic agents of several diseases of humans, such as leishmaniasis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Leishmania

 

a genus of protozoans of the class Mastigophora.

Several species of Leishmania are known, although most are parasites of reptiles. Three species (L. donovani, L. tropica, and L. brasiliensis) are intracellular parasites of man and some animals, such as dogs. The organisms are transmitted by bloodsucking insects (sandflies of the genus Phlebotomus). L. donovani and L. tropica are found in the tropics and subtropics of Eurasia; L. brasiliensis is found in Central and South America. L. donovani is the causative agent of visceral leishmaniasis, or kala-azar, a serious disease of man that is widespread in India, China, and Sumatra; in the USSR, it appears from time to time in Middle Asia.

Leishmanias localize in the cells of the reticuloendothelial system, including those of the lymph nodes. The body is pear-shaped, 2–4 µm long, and has one nucleus and a kinetoplast. In the body of the animal host, the organism develops into a flagellate leptornonad form.

L. tropica, the causative agent of cutaneous leishmaniasis (Penjdeh sore), is morphologically similar to L. donovani. In the USSR, it is found in Middle Asia and Transcaucasia.

IU. I. POLIANSKII

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The associations of Leishmania major and Leishmania tropica aspects by focusing their morphological and molecular features on clinical appearances in Khuzestan province, Iran.
Compound (2a) at different test concentrations of 0.0075, 0.015, 0.031, 0.062, 0.125, 0.25, 0.5, 1 mg/mL shows 0.7 +- 0.7, 11.7 +- 2.9, 29.0 +- 3.1, 49.7 +-3.0, 72 +- 2.5, 82.3 +- 1.3, 95.7 +- 1.5 and 100 +- 0.0 % growth inhibition of Leishmania tropica promastigotes.
Involvement of thiol metabolism in resistance to glucantime in Leishmania tropica. Bioch Pharma 1998; 56(9): 1201-8.
A nested PCR-based schizodeme method for identifying Leishmania kinetoplast minicircle classes directly from clinical samples and its application to the study of the epidemiology of Leishmania tropica in Pakistan.
Anthroponotic cutaneous leishmaniasis in Kabul, Afghanistan: the low susceptibility of Phlebotomus papatasi to Leishmania tropica. Trans.
Both leishmania major and leishmania tropica cause the cutaneous form of the disease, which can produce lingering boils such as the ones that popped up all over Mason AlsalehAAEs body.
Carbocyclic inosine as a potent antileishmanial agent: the metabolism and selective cytotoxic effects of carbocyclic inosine in promastigotes of Leishmania tropica and Leishmania donovani.
In addition, in light of the recent announcement by the Department of Defense and the American Association of Blood Banks regarding the possible risk of transfusion-transmitted leishmaniasis, a few words will also be said about Leishmania tropica. * Malaria.
Simdiye dek yapilan calismalarla hastaligin etkeninin Leishmania tropica'nin farkli zimodemleri oldugu ayni zamanda Leishmania infantum'un da KL'ye sebep olabildigi gosterilmistir (5).
Cutaneous leishmaniasis (CL), the most widespread form of leishmaniasis, caused by Leishmania tropica and L.
The promastigotes form of the Leishmania tropica KMU 25 (isolated from a patient and identified by Khyber medical University, KP, Pakistan) were grown in M199 medium with 10% fetal bovine serum (FBS), HEPES buffer, streptomycin, and penicillin.