Notably, the abundance of four types of bacteria - low levels of Haemophilus and Porphyromonas and high levels of Leptotrichia
and Fusobacterium - could distinguish pancreatic cancer patients from healthy individuals.
Subjects with higher alcohol consumption had certain genera that were enriched, including Actinomyces, Leptotrichia
, Cardiobacterium, and Neisseria; some of these genera contain oral pathogens, and Neisseria can synthesize alcetaldehyde from ethanol.
Prevotella, Bacillus, Bacteroides, Staphylococcus, and Porphyromonas were abundant in Group A, whereas Prevotella, Streptococcus, Veillonella, Leptotrichia
, and Lactobacillus were abundant in Group B.
conducted a cross-sectional study showing an increase in Leptotrichia
Pseudomonas and Streptococcus are facultative anaerobes; Peptostreptococcus, Fusobacterium, Leptotrichia
, and Parvimonas are obligate anaerobes.
However, they did not find any significant difference in the overall microbial composition of the conjunctiva and tongue between SS patients and healthy controls, although there was a prevalence of Streptococcus and a decrease in Leptotrichia
and Fusobacterium levels in the SS tongue samples.
Zhang more recently found an enzyme in the bacterium Leptotrichia
shahii that could tinker with RNA.
Antimicrobial, antioxidant, hepatoprotective and antitumor properties of these microorganisms (Actinomyces meyeri, Actinomyces odontolyticus, Bacteroides ovatus, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium dentium, Clostridium butyricum, Clostridium beijerinckii, Enterococcus gallinarum, Enterococcus faecalis, Escherichia coli, Eubacterium aerofaciens, Eubacterium lentum, Lactobacillus spp., Leptotrichia
buccalis, Micrococcus spp., Neisseria mucosa, Peptostreptococcus asaccharolyticus, Sarcina spp., Staphylococcus xylosis, Staphylococcus cohni, Staphylococcus capitis, Streptococcus agalactiae) have been only subsequently studied, and each of the strains was assigned a number from No.1 to No.
Results showed that patients diagnosed with pancreatic cancer had higher levels of two particular oral bacteria, Leptotrichia
and Campylobacter, when compared to any other healthy or diseased state including non-cancerous pancreatic disease.