Leukoplakia

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Related to Leucoplakia: leukoplakia vulvae

leukoplakia

[‚lü·kō′plā·kē·ə]
(medicine)
Formation of thickened white patches on mucous membranes, particularly of the mouth and vulva.

Leukoplakia

 

milky-white spots (radius, to 0.5 cm) on the mucous membranes near the skin (for example, on the lower lip) and on the cheeks, tongue, bottom of the mouth, esophagus, cervix uteri, vagina, and urinary bladder.

Leukoplakia is one of the precancerous diseases. Smoking, advanced tooth decay, excessive consumption of alcohol or spices, certain inflammations of the oral cavity, avitaminosis A or B complex, and poorly fitting metal dental bridges, fillings, and crowns may give rise to leukoplakia. The disease occurs in two forms. In simple leukoplakia, the mucous membrane is smooth; its surface resembles mosaic or parquetry. This may be complicated by fissures or erosions. In verrucose leukoplakia, the mucosa is raised and the color varies from pearly to chalky. Patients complain of sensations of petrifaction, burning, and tenderness. Treatment is by surgical removal, electrocoagulation, or radiation therapy.

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HIV infection has several oral manifestations, including oral candidiasis and oral hairy leucoplakia. Occasionally unusual presentations requiring rigorous investigations are seen, and in these cases the diagnosis sometimes remains a dilemma owing to limited investigation facilities.
[31.] Schepman KP, Van der Meij EH, Smeele LE, Van der Waal I: Prevalence study of oral white lesions with special reference to a new definition of oral leucoplakia. Eur J Cancer 1996;32B(6):416-9.
In the present observational study, among malignant tumours squamous cell carcinomas were recorded higher in number, whereas premalignant leucoplakia was the common presentation.
OSMF was the most common precancerous condition encountered in our study whereas Leucoplakia turned out to be the commonest precancerous lesion in our survey.
Cutaneous manifestations of diabetes are classified into four categories: Skin lesions with strong-to-weak association to diabetes (necrobiosis lipoidica, diabetic dermopathy, diabetic bullae, yellow skin, eruptive xanthomas, perforating disorders, acanthosis nigricans, oral leucoplakia, lichen planus), infections (bacterial, fungal), cutaneous manifestations of diabetic complications (microangiopathy, macroangiopathy, neuropathy) and skin reactions to diabetic treatment (Sulphonylureas or insulin).
In the long incubation period between the initiation of carcinogenic habits and development of invasive oral cancer, well-defined oral precancerous lesions such as leucoplakia, submucous fibrosis, and erythroplakia occur.
Other infective dermatoses seen were herpes zoster and pityriasis versicolor in 2 (1.1%); primary chancre, scrofuloderma and oral hairy leucoplakia in 1 (0.5%) Table 2.