leukocidin

(redirected from Leukocidins)
Also found in: Medical.

leukocidin

[‚lü·kə′sīd·ən]
(biochemistry)
A toxic substance released by certain bacteria which destroys leukocytes.
References in periodicals archive ?
Staphylococcus aureus hemolysins, bi-component leukocidins, and cytolytic peptides: a redundant arsenal of membrane-damaging virulence factors?
aureus leukocidins targeted by ASN-1, one of the two antibodies in the company's lead product candidate, ASN100.
Faghri, "Prevalence of genes encoding bi-component leukocidins among clinical isolates of methicillin-resistant Staphylococcus aureus," Iranian Journal of Public Health, vol.
Panton-Valentine leukocidin (PVL) is one of the most important virulence factors of S.
aureus leukocidins responsible for lysis of human phagocytic (immune) cells: Panton-Valentine leukocidin, leukocidin ED, and gamma-hemolysins AB and CB.
The prevalence of genes encoding leukocidins in Staphylococcus aureus strains resistant and sensitive to methicillin isolated from burn patients in Taleghani Hospital, Ahvaz, Iran.
coli, and [alpha]-hemolysin, y-hemolysin, and the leukocidins from S.
These include some that most clinicians may recognize, e.g., staphylococcus protein A (a super antigen), leukocidins, and coagulase itself.
These include some that most clinicians may recognize, for example, staphylococcus protein A (a super antigen), leukocidins, and coagulase itself.
aureus isolates also produce one or more additional exoproteins, such as toxic shock syndrome toxin-1 (TSST-1), staphylococcal enterotoxins (SEs), exfoliative toxins (ETs), and leukocidins. (2-4) Recently, Panton-Valentine leukocidin (pul) encoded by two contiguous and cotranscribed genes (lukS-PV and lukF-PV) is an important virulence factor for community-acquired MRSA (CA-MRSA) affecting individuals without apparent risk factors for hospital acquisition.
Using polymerase chain reaction (PCR), we determined the presence of accessory gene regulator (ago allele group (1-4), SCCmec element (I-IV, according to the designation of Oliveira [15]), and 22 specific staphylococcal virulence genes (including 16 super-antigenic toxins, 3 hemolysins, and 3 leukocidins), as described previously (16).
To the Editor: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), which carries genes for Panton-Valentine leukocidin (PVL), has become a major concern worldwide (1-3).