Levomycetin

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Levomycetin

 

(chloramphenicol, Chloromycetin, Paraxin, Pharmycetin), a broad-spectrum antimicrobial antibiotic isolated in 1947 from a culture fluid of the actinomycete Streptomyces venezuelae. Levomycetin was also synthesized chemically, and this has become the principal method of obtaining it.

Levomycetin has a high level of activity and is only slightly toxic to man. The antibiotic Synthomycetin is a mixture (racemate) of the optical isomers of levomycetin, of which only the levorotatory isomer is active. In medical practice, levomycetin is taken internally as tablets; for eye diseases, it is used as drops. Levomycetin stearate, which does not have the bitter taste characteristic of levomycetin, is used mainly in pediatrics.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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