A new variant in signal peptide of the human luteinizing hormone receptor (LHCGR) affects receptor biogenesis causing leydig cell
The values of primary testis volume, absolute Cavalieri testis volume, the volume of seminiferous tubule epithelium and lumen, the significant increase (P=0.008) in the total number of Leydig cells
compared to the control group.
Nitric oxide: An autocrine regulator of Leydig cell
steroidogenesis in the Asian catfish, Clarias batrachus.
The CYP17 in the testis was exclusively localized in Leydig cell
of the interstitial compartment (Figure 5C, Table 3).
Effect of retinol and retinoic acid on testosterone production by rat Leydig cells
in primary culture.
(A,B) Steroidogenic Leydig cells
were labeled by immunostaining of CYP11A1 in cultured explants of gestational week (GW) 10-12.
The researchers reasoned that the direct conversion of adult skin cells into Leydig cells
would be a faster, safer regenerative medicine approach.
Zirkin, "Temporal relationships among testosterone production, steroidogenic acute regulatory protein (StAR), and P450 side-chain cleavage enzyme (P450scc) during Leydig cell
aging," Journal of Andrology, vol.
 demonstrated that fetuses with PBS had marked Leydig cell
hyperplasia in contrast to the other groups.
Zirkin, "Age-related decreases in Leydig cell
testosterone production are not restored by exposure to LH in vitro," Endocrinology, vol.
The positive cells were found in the Leydig cells
or ovarian granular cells.
Increased proliferation of Leydig cells
induced by neonatal hypothyroidism in the rat.