"What we would like to do is identify some of the most abundant of these reactive intermediates that are formed tinder representative conditions either in vitro or in animal models in vivo, where we can manipulate oxidative stress," says Liebler.
"I think MS is becoming increasingly powerful, and we haven't yet realized the full power of these tools," says Liebler. "On the other hand, I think MS-based proteome analyses will give way to other kinds of less high-tech approaches, using perhaps some variants of array technologies: arrays of antibodies or aptamers [basic nucleic acid equivalents of antibodies] and perhaps small molecules that recognize proteins--little lab-on-a-chip devices that would be suitable for analysis of some components of proteins." There are a lot of competing technologies, he says, and it's hard to say what's going to work--"but if the last ten years have taught us anything, it's that we should be prepared to be surprised, regularly."
"Previous work had suggested that pheomelanin could be a wolf in sheep's clothing," says Liebler.
"Correct patellar alignment is one of the most important factors among all the things that determine the physical potential of the dancer," says Liebler.
"Patella problems can be seen in students seven to nine years of age or younger; they worsen, if uncorrected, in the early teens.
It will continue to operate under its current leadership team led by Gar Liebler.
The company's six offices across Michigan, North Carolina and South Carolina now fall under the Associa umbrella but will continue operating at the local level under the same company name.
Hines asserts that the outreach program wouldn't succeed nearly as well without the support of the center and especially its director, Dan Liebler.
Liebler plays an important role in setting the center tone for outreach, as well as scientist involvement with outreach, says Hines.