pleural effusion

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Related to Light's criteria: pleural effusion, Meigs syndrome, SAAG

pleural effusion

[‚plu̇r·əl i′fyü·zhən]
(medicine)
Abnormal accumulation of fluid in the area between the membranes lining the lungs and the chest cavity (the pleural space).
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References in periodicals archive ?
Present study shows that using pleural fluid cholesterol to differentiate exudate and transudate was more sensitive and specific than using Light's criteria because in our study 1 exudate out of 52 exudates was misclassified as transudate (Sensitivity 98%) and 1 out of 8 transudates was erroneously labelled as exudate (Specificity 87.
Table 6 shows comparison of sensitivity, specificity, positive predictive value and negative predictive value when using Light's criteria to differentiate exudate and transudate and when using pleural fluid cholesterol to differentiate exudate and transudate among various studies.
1) In general, Light's criteria correctly identify exudates but may misclassify 20 percent to 25 percent of transudates as exudates.
Diagnostic parameters mentioned in Light's criteria were performed from PF and serum, whereas parameters of the new criteria used in our study (LDH, TP, and ADA) were performed from PF.
Results: After using multiple parallel tests, the sensitivity, specificity, and accuracy of Light's criteria for diagnosing exudates were 98.
The modified Light's criteria should be used to classify the fluid as either an exudate or a transudate.
The misclassification of transudates and exudates were less pleural fluid to serum cholinesterase ration, compared to all other parameters and Light's criteria.
It has been conducted to study the significance of Pleural fluid LDH, Cholesterol and ADA levels in comparison to light's criteria for rapid and accurate evaluation of pleural effusion especially the exudates.
In 21 patients, pleural effusions were clinically attributed to heart failure; however, 14 of these 21 patients were classified as exudates by Light's criteria.
Hence, this study was undertaken to evaluate the diagnostic efficacy of pseudocholinesterase levels in pleural fluids and the fluid to serum ratio of pseudocholinesterase in differentiation between transudates and exudates and compare it with Light's criteria.
1) However Light's criteria may differentiate certain transudative effusion as exudative effusion.