Linalool


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Related to Linalool: limonene, geraniol

linalool

[lə′näl·ə‚wȯl]
(organic chemistry)
(CH3)2C:CH(CH2)2CCH3OHCH:CH2 A terpene that is a colorless liquid, has a bergamot odor, boils at 195-196°C, and is found in many essential oils, particularly bergamot and rosewood; used as a flavoring agent and in perfumes. Also known as coriandrol.

Linalool

 

2,6-dimethyl-2,7-octadiene-6-ol, a terpene alcohol:

(CH3)2CCHCH2CH2C(CH3) (OH) CHCH2

A colorless liquid with a lavender odor. Boiling point, 198°-200°C; density, 0.862–0.865 g/cm3 at 20°C. Linalool exists in two optically active (+) and (-) forms, as well as the (±) form (a racemic mixture). It is readily converted into geraniol upon action of organic acids and into a mixture of terpineols in the presence of sulfuric acid. Linalool oxidizes to form citral.

Linalool is part of many essential oils (for example, coriandrol) in free form and as esters of acetic acid (linalyl acetate) and butyric acid; the rectification process is used to extract linalool from essential oils. Linalool may also be synthesized from acetylene and isoprene, as well as from α-pinene. Linalool and linalyl acetate are widely used as odoriferous substances in perfume and cosmetics manufacture.

References in periodicals archive ?
Interestingly, the hybrid tambacu (Piaractus mesopotamicus males x tambaqui females) only reached deep anesthesia with EOLA-L (47.66% linalool) at a concentration of 75 [micro]L/L in approximately 5.5 min, however time to induce deep anesthesia was a little longer than 1 min at 200 [micro]L/L (SENA et al., 2016).
Carson and Riley (1995) and Peana and Moretti, 2002 have demonstrated that Linalool is effective against Candida albicans, Escherichia coli, and Staphylococcus aureus, but not against Pseudomonas aeruginosa.
In EO studies of coriander, Beyzi and Gurbuz (2014) reported that linalool was the major component (78.94 to 85.66%) and essential oil components were I3-terpinene and camphor in CS, respectively.
Standardization of "Lavaflam" tablets was performed based on the following parameters: appearance, geometric size, average weight, disintegration, abrasion resistance, compressive strength, assay (the amount of flavonoids was calculated in recalculation in isosalipurposide, lavender oil - in linalool and linalool acetate).
Thymol, linalool, and citronellol were obtained, along with technical product information (Table 1), from Quinari[R], which produces and sells essential oils and derivatives on an industrial scale.
In a study, linalool (60.72%) was characterized as the major compound in the essential oil of Mentha piperita L.
However, major active component of coriander seeds was linalool, whilst, coriander leaves possess more phenolic compounds as compared to seeds.
Moreover, according to a number of experts, linalool is a competitive N-methyl-D-aspartate (NMDA) receptor antagonist and the blockage of glutamate NMDA receptor contributes to its antiepileptic properties.
verum Component HD MWHD [gamma]-Terpinene 3.20 (5.336) Linalool 2.12 (5.856) 2.13 (5.856) Cinnamaldehyde 67.97 (8.259) 89.25 (8.568) Thymol 3.39 (8.855) 3.40 (8.859) Carvacrol Eugenol 2.73 (9.842) Caryophyllene 1.46 (11.281) % relative abundance ([t.sub.R], min) T.
By the end of the fermentation of Criollo cacao (3 days), predominant amounts of volatiles with floral, fruity, and woody aromas including linalool, epoxylinalool, benzeneethanol, pentanol acetate, germacrene, a-copaene, aromadendrene, 3,6-heptanedione, butanal, 1-phenyl ethenone, 2-nonanone, and 2-pentanone were detected.
Another monoterpenoid that deserves attention is linalool, as recent studies have suggested a potential anesthetic activity in fish (3,10).