linkage disequilibrium

(redirected from Linkage equilibrium)
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linkage disequilibrium

[¦liŋ·kij dis‚ē·kwə′lib·rē·əm]
(genetics)
The occurrence in a population of certain combinations of linked alleles in greater proportion than expected from the allele frequencies at the loci.
References in periodicals archive ?
In population genetics, linkage equilibrium and linkage disequilibrium describe linkage of alleles at different loci.
This program also computes the linkage equilibrium between each pair of loci based on a likelihood-ratio test (Slatkin and Excoffier 1996).
After correcting allele frequencies for putative null alleles, a significant deviation from linkage equilibrium was detected with GENEPOP for only one pair of loci: Med 362 / Med 722 (P < 0.
We recently demonstrated linkage equilibrium between tightly linked molecular markers and the Ms locus in open-pollinated populations of onion (Gokce and Havey, 2002).
These formulas, however, assume linkage equilibrium and Hardy-Weinberg equilibrium.
If all the loci are in linkage equilibrium, then the frequencies of combinations of alleles are products of allele frequencies, and
2] testcrossed to H93 x B99, if either of two conditions was met (Melchinger, 1988): (i) epistasis was absent; or (ii) epistasis was present but the parental populations were in linkage equilibrium.
Bazykin (1973) provides the conditions for the existence of a migration-selection balance using a two-locus model of stabilizing selection with equal migration rates under the assumption of linkage equilibrium.
Additive variance assuming linkage equilibrium was [MATHEMATICAL EXPRESSIONS NOT REPRODUCIBLE IN ASCII] in the initial generation.