Multiple symmetric lipomatosis
may be the consequence of defective noradrenergic modulation of proliferation and differentiation of brown fat cells.
The diagnosis of mediastinal lipomatosis
is generally made by observation of mediastinal enlargement on chest graphy and demonstration of intensity changes related to fat on CT or MR imaging.
Diagnosis of Spinal Epidural Lipomatosis
(SEL) secondary to the chronic use of steroids was made and the patient underwent T5-7 laminectomy with removal of the epidural fat.
CT scan, however, revealed extensive mediastinal lipomatosis
, with compression but no invasion of adjacent structures.
The final pathology was fatty fibroconnective tissue, consistent with epidural lipomatosis
Crayton HE, Partington CR, Bell CL: Spinal cord compression by epidural lipomatosis
in a patient with systemic lupus erythematosus.
Coexistence of XGP and renal replacement lipomatosis
as well as XGP with renal TB has been reported.
There was no evidence of accompanying emphysema or lipomatosis
Imaging studies can distinguish encapsulated fat (progressive nodular lipomatosis
and multiple hereditary lipomas, hibernoma) from Madelung disease by means of fat suppression and chemical shift imaging.
is an uncommon disorder defined as a pathologic overgrowth of normal epidural fat.
The histologic picture corresponds to sheets of hypocellular dense collagen, with interspersed mature fat, small vessels, and entrapped nerve fibers; since it is not composed of fibrocartilage, it resembles more of a fibrolipoma, lipomatosis
, scar, or elastofibroma.
To the best of our knowledge, this is only the second case of laryngeal lipoma associated with lipomatosis
to be reported in the English-language literature.