lipophobic


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lipophobic

[‚lip·ə′fōb·ik]
(chemistry)
Lacking an affinity for, repelling, or failing to absorb or adsorb fats.
References in periodicals archive ?
Many of these substances show lipophobic characteristics which could be used for therapeutics diseases neurosensory organs [103].
The mechanism of enhanced oil recovery using lipophobic and hydrophilic polysilicon (LHP) nanoparticles ranging in size from 10 to 500 nm for changing the wettability of porous media is analyzed theoretically in [3].
Madam, cetirizine hydrochloride, an antihistamine, is the active constituent of Zyrtec(r) that functions as competitive peripheral H1 receptor inhibitor.1 Cetirizine is known to have reduced blood-brain barrier penetration due to its larger mass, lipophobic properties and increased attraction for peripheral H1 receptors.
As an example application, poly(tetrafluoroethene) is hydrophobic and lipophobic. Accordingly, polymers possessing a perfluoroalkyl side chain with an appropriate length are used for water and oil repellents and surface modifiers.
The greater drug penetration enhancing activity of solution may be attributed to the combined effects of both lipophilic and lipophobic domains of solutions (Yamada et al.,1987; Obata et al., 1991).
Shimomura, "Superhydrophobic and lipophobic properties of self-organized honeycomb and pincushion structures," Langmuir, vol.
These lipophobic ("fat-fearing") statins are reluctant to dissolve into cell membranes.
The results revealed that lipophilic enhancers were more effective than lipophobic ones [27] and in simple diffusion experiments, this is very difficult to reveal possible interactions and it could be irrational to try and do so.
As an added benefit, the lean meat they produced appealed to lipophobic Americans.
They also showed in vitro that ER-negative human breast cancer cell lines were more sensitive to lipophilic statins than ER-positive cells, and that lipophobic statins--namely, pravastatin and rosuvastatin--didn't inhibit growth of the malignant cells.
(1) In this lipophobic society, an ideal body model is thin for women and muscular for men.
PFCs are both lipophobic and hydrophobic; thus, after absorption they will bind to proteins in serum and liver rather than accumulate in lipids.