biopsy

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Related to Liver biopsy: liver disease, liver cancer

biopsy

(bīäp`sē), examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended. Incisions may be made and total or partial lesions removed in the form of wedges or cylindrical pieces, or scrapings of the surface membranes of internal organs may be collected. Needlelike instruments may be used to pierce the tissues and remove soft inner material. Once the tissue specimen has been obtained it is fixed, i.e., membrane proteins and enzymes are stabilized and chemical and histologic analyses are carried out by pathologists. Tumors are routinely biopsied in order to determine whether they are malignant. Fine needle aspiration is a technique more readily used for certain tumors or lesions because it is less expensive and damaging than traditional surgical biopsy.

biopsy

[′bī‚äp·sē]
(pathology)
The removal and examination of tissues, cells, or fluids from the living body for the purposes of diagnosis.

biopsy

1. examination, esp under a microscope, of tissue from a living body to determine the cause or extent of a disease
2. the sample taken for such an examination
References in periodicals archive ?
Contract notice: Delivery of endoscopic equipment and liver biopsy kits - 4 packages.
A RETIRED publican died from complications after a liver biopsy, an inquest heard.
Our study has found that Fibroscan, in comparison to liver biopsy, can predict liver fibrosis with 90 per cent accuracy in early and late stages of liver disease at one- third of the cost.
While metabolic syndrome occurs in 28% of the HCV-negative population with NAFLD, Italian researchers found that metabolic syndrome was only present in 6% of those with both NAFLD and genotype 1 or 2 HCV infection (18) Those with HCV/NAFLD were more likely to be insulin resistant (elevated fasting glucose and elevated fasting insulin), be male, and have fibrosis on liver biopsy than their NAFLD counterparts without HCV.
Testing for HEV infection is recommended during initial assessments of posttransplant hepatic dysfunction because histologic appearances in liver biopsy specimens may not clearly distinguish between graft rejection and acute viral hepatitis (Figure, panels A, B).
The clinical utility of biomarkers and the nonalcoholic steatohepatitis CRN liver biopsy scoring system in patients with nonalcoholic fatty liver disease.
Has a liver biopsy obtained within 3 years (36 calendar months) prior to the Day 1 visit, with a fibrosis classification of noncirrhotic as judged by a local pathologist (defined as Knodell ≤3, Metavir ≤2, Ishak ≤4, or Batts and Ludwig ≤2).
Her liver biopsy was consistent with confluent hepatic necrosis with collapse.
6 Liver biopsy - a small sample of tissue is taken for microscopic examination to look for liver disease.
Liver biopsy has traditionally been considered the standard for assessing liver fibrosis severity but this invasive method has major drawbacks including significant incidence of morbidity, procedure and hospitalization costs, and clinical shortcomings as fibrosis is underestimated in 10- 30% of the cases.
A liver biopsy should be obtained in all HCV-positive individuals regardless of the aminotransferases levels, as they have been documented to have no relationship with the severity of the histological findings in a given individual.
A liver biopsy specimen demonstrated an unanticipated and uncommon finding of numerous intraparenchymal collections of histiocytes associated with numerous fungi in yeast forms.