Lobeline


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Related to Lobeline: hydrastine

lobeline

[′lō·bə‚lēn]
(pharmacology)
C22H27NO2 A crystalline compound isolated from the herb and seeds of Indian tobacco (Labelia inflata); melting point is 130-131°C; soluble in hot alcohol, chloroform, and benzene; used in medicine as a respiratory stimulant.

Lobeline

 

an alkaloid contained in plants from the genus Lobelia; it is a respiratory stimulant. In medicine, lobeline hydrochloride is used in a solution, which is injected intravenously or intramuscularly. It is indicated for respiratory standstill or weakening of respiratory activity. Lobeline is sometimes used diagnostically to determine the circulation rate.

References in periodicals archive ?
Lobeline (5-10 mg/kg i.p.) did not affect the levels of AST, ALT, ALP, and LDH after 4 days of exposure [99].
Dos Santos et al., "Evaluation of mutagenic and genotoxic activities of lobeline and its modulation on genomic instability induced by ethanol," Life Sciences, vol.
A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse.
Respiratory responses of mature horses to intravenous lobeline bolus.
It's a psychological approach that consists of an audio cassette, a book and lobeline sulfate (a nicotine substitute that is a derivative of the Indian tobacco plant) tablets."
Lobeline. a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells.
Lobeline sulfate products have been sold over the counter for a number of years under such trade names as Nikoban and Bantron.
Cigarrest appears to combine lobeline sulfate with vitamins.
The effects of D-amphetamine, meprobamate and lobeline in the cigarette smoking behavior of normal human subjects.
Lobeline, a piperidine alkaloid from Lobelia inflata and several other Lobelia species, inhibited P-gp activity.
Keywords: Lobeline; Multidrug resistance (MDR); ABCB1 gene; P-glycoprotein (P-gp)
Lobeline, a piperidine alkaloid, which is produced by Lobelia inflata (family Lobeliaceae) and several other Lobelia species, stimulates chemoreceptors in carotid and aortic bodies, and then exerts reflectory activation of respiratory centre (Fig.