Luteinizing Hormone


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luteinizing hormone

[′lüd·ē·ə‚nīz·iŋ ′hȯr‚mōn]
(biochemistry)
A glycoprotein hormone secreted by the adenohypophysis of vertebrates which stimulates hormone production by interstitial cells of gonads. Abbreviated LH. Also known as interstitial-cell-stimulating hormone (ICSH).

Luteinizing Hormone

 

(LH; also, interstitial cell-stimulating hormone, or ICSH), one of the gonadotropic hormones secreted by the anterior pituitary.

Chemically, LH is a glycoprotein whose physical and chemical properties differ from species to species (in sheep, the molecular weight of LH is 40,000; in swine, 100,000). In females, LH stimulates the growth of the follicles in the stages preceding estrus and ovulation, in ovulation, and during the formation of the corpus luteum. A deficiency of LH in rats and guinea pigs leads to continuous estrus, a result of the abnormal enlargement of the follicles that did not undergo ovulation. The action of follicle-stimulating hormone (FSH) on the follicle is necessary before LH can exert its influence on the ovary. Ovulation, which is induced by LH, depends on the stage of follicular development, for which both the action time of LH and an optimal ratio of LH to FSH are important. For example, in cats and rabbits, the most effective ratio is 1:100. In males, LH stimulates interstitial testicular tissue and the secretion of the male sex hormone testosterone.

V. M. SAMSONOVA

References in periodicals archive ?
A syndrome of gonadotropin resistance possibly due to a luteinizing hormone receptor defect.
Characterization of the luteinizing hormone beta (LH[beta]) subunit gene in the Indian River buffalo (Bubalus bubalis).
A controlled study of human chorionic gonadotrophin induced ovulation versus urinary luteinizing hormone surge for timing of intrauterine insemination.
Intracerebroventricular infusion of leptin elevates the secretion of luteinizing hormone without affecting food intake in long-term food-restricted sheep, but increases growth hormone irrespective of bodyweight.
Studies involved analysis of parameters such as DHEA-S, testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH), progesterone, and 17-beta-Estradiol (E2) were assayed by the Architect i2000 analyzer (Abbott Laboratories, Chicago, IL), which employed chemiluminescent microparticle immunoassay (CMIA) method.
Effect of basal serum luteinizing hormone and luteinizing hormone/follicle-stimulating hormone ratio on outcomes of in vitro fertilization-embryo transfer in patients with polycystic ovarian syndrome.
Utility of Basal luteinizing hormone levels for detecting central precocious puberty in girls.
Failure to achieve castrate levels of testosterone during luteinizing hormone releasing hormone agonist therapy: the case for monitoring serum testosterone and a treatment decision algorithm.
Examination Stress Decreases Plasma Level of Luteinizing Hormone in Male Students, Psychosomatic Medicine, 50: 286-294.
The mean values of the hormonal assays for azoospermia were: 21.84+-1.94 (luteinizing hormone), 14.14+-4.4 (follicle-stimulating hormone), 23.95+-17.43 (testosterone), and 15.03+-2.91 for prolactin.
It also normalized levels of prolactin and luteinizing hormone, Dr.
Although a urinary testosterone/ luteinizing hormone ratio [greater than or equal to] 30 is a diagnostically sensitive marker for anabolic steroids (4), the combination of increased testosterone and undetectable luteinizing hormone in plasma suggests exogenous use.

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