Lysergic Acid

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Related to Lysergic Acid: Lysergic acid amide

lysergic acid

[lə′sər·jīk ′as·əd]
(organic chemistry)
C16H16N2O2 A compound that crystallizes in the form of hexagonal plates that melt and decompose at 240°C; derived from ergot alkaloids; used as a psychotomimetic agent.

Lysergic Acid


an organic acid of complex structure (C16H16O2N2) containing an indole residue. Lysergic acid crystals have a melting point of 238°C.

Lysergic acid is found in a number of ergot-generated alkaloids (ergoalkaloids), from which it can be isolated by alkaline hydrolysis. The first complete synthesis of lysergic acid was accomplished in 1954 by R. Woodward. The characteristic biological action of lysergic acid—the contraction of the uterine muscles—is expressed more weakly with lysergic acid itself than with the ergoalkaloids. On entering the organism, lysergic acid diethylamide, known as LSD, is an antagonist of serotonin, a central nervous system regulator. LSD has a strong hallucinogenic effect and is used in the treatment of certain mental diseases.

References in periodicals archive ?
of Participating Laboratories in 2008, n = 3 survey Drug or Class of Drugs mailings Amphetamines 2844 MDMA 371 Barbiturates 2765 Benzodiazepines 2719 BE/Cocaine 2830 THC 2767 Ethanol 523 Methadone 1232 Methaqualone 110 Opiates 2781 Oxycodone 267 Phencyclidine 2325 Propoxyphene 468 Tricyclics 1121 LSD 14 Abbreviations: BE, benzoylecgonine; LSD, lysergic acid diethylamide; MDMA, methylenedioxymethamphetamine; THC, tetrahydrocannabinol.
Anthony's fire had hallucinations, an effect of the poisoning and the lysergic acid.
Always cover marijuana, opiates (heroin and pharmaceuticals), lysergic acid diethylamide (LSD or acid), phencyclidine hydrochloride (PCP or angel dust), psilocybin mushrooms, mescaline, [gamma]-hydroxybutyrate (GHB) and other sedative-hypnotics, 3,4-methylenedioxymethamphetamine (MDMA or ecstasy), and cocaine and other stimulants, including those prescribed for ADHD.
Combination use with cannabis is common (6), and MDMA is popular with other recreational psychedelics such as lysergic acid diethylamide (LSD) ("candy flipping" or "trolling"), mushrooms ("flower flipping"), and LSD and mushrooms ("triple flipping").
Chemical Warfare Secrets Almost Forgotten is also an excellent resource on the effects of incapacitating chemical agents, with firsthand accounts of human exposure to lysergic acid diethylamide (LSD), 3-quinuclidinyl benzilate (BZ), and other agents.
Padilla was given drugs against his will, believed to be some form of lysergic acid diethylamide (LSD) or phencyclidine (PCP), to act as a sort of truth serum during his interrogations.
A Damien Hirst print, entitled Lysergic Acid Diethylamide, was expected to sell at between pounds 8,000 and pounds 10,000, while an Alexander Millar oil painting, Goal, was given an estimate of pounds 10,000 - pounds 12,000.
Pepper, Elmer Gantry, and Jim Jones of lysergic acid.
IN JANUARY the Swiss inventor of lysergic acid diethylamide, Albert Hofmann, turned 100 and was honored at a Basel symposium called "LSD: Problem Child and Wonder Drug" Hofmann first synthesized the hallucinogen in 1938, and the pharmaceutical giant Sandoz (now Novartis) began marketing the drug as a treatment for psychological problems a decade later.
dagger]) Viagra[R], ecstasy, nitrites, lysergic acid diethylamide (LSD), or gamma hydroxybutyrate (GHB).