Lysolecithin


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Lysolecithin

 

(l-acylglycero-3-phosphorylcholine), the product of the removal of a single fatty acid molecule from lecithin; a phospholipid fraction.

Small quantities of lysolecithin are found in many animal and plant tissues. The richest sources are blood and the adrenal glands. Lysolecithin forms in the organism from lecithin under the influence of the enzyme phospholipase. It alters the permeability of biological membranes, induces the hemolysis of erythrocytes, regulates the permeability of vascular walls, and reduces cardiac sensitivity to acetylcholine. In the organism, lysolecithin is found in the form of a compound with albumin and cholesterol. (The latter reduces lysolecithin’s biological activity.)

References in periodicals archive ?
9) The enzyme attacked only lysolecithin but not lecithin.
These are also transported after being mixed with lipid micelles formed with the aid of bile salts, lysolecithin, lower glycerides, and cholesterol.
2] contained in Lp(a) cleaves the excessively abundant oxidized phospholipids derived from dietary chylomicrons and remnant lipoproteins bound to their particles and releases short-chain fatty acids and lysolecithin (12).
Impairment of endothelial-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins.
Lecithin and/or lysolecithin is added to an animal feed including an exogenous enzyme to boost the performance of the enzyme so that a desired level of performance can be maintained while reducing the amount of exogenous enzyme that must be included in the animal feed.
Germinally transgenic tadpoles were produced by restriction enzyme-mediated integration nuclear transplantation according to Kroll and Amaya (1996), with the following modifications: sperm was purified by centrifugation on a two-layer discontinuous Percoll (Sigma) gradient before the permeabilization step, which was performed with digitonin (Sigma) instead of lysolecithin.
By converting the lecithin in eggs into lysolecithin, Maxapal A2 helps to produce an emulsion with high physical stability, high viscosity, exceptional heat stability and extended shelf life.
These bipyramidal-shaped crystals are composed of the enzyme lysolecithin acylhydrolase, one of several eosinophilic proteins that damage respiratory epithelium and contribute to the pathology of allergy in the upper respiratory tract.
And the smoke appeared to trigger an increase in lysolecithin in the lung (a toxic compound also found in snake venom) which shot holes in lung membranes.
However, as most quaking mouse nerve fibers have a minimal sheathing with myelin, the scientists had to create focal areas completely denuded of myelin by injecting lysolecithin before transplantation.