monoamine oxidase inhibitor

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monoamine oxidase inhibitor

[män·ō′am‚ēn ′äk·sə‚dās in′hib·əd·ər]
(pharmacology)
Any drug, such as isocarboxazid and tranylcypromine, that inhibits monoamine oxidase and thereby leads to an accumulation of the amines on which the enzyme normally acts.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
This is not incompatible with the neuroprotective activity of the stilbene since it has been proposed that neuroprotection is not linked to MAO inhibition, even for various MAO inhibitors [9, 11].
The authors argue that the combination of a MAO inhibitor with another centrally active serotonergic agent poses significant health risks from MAO inhibitor poisoning or serotonin syndrome.
The partial alleviation of depressive symptoms with fluoxetine in rats in particular, demonstrated the extent and stability of the depressive effect of immunization with MAO inhibitors.
A tyramine-free diet is necessary with the use of an MAO inhibitor, beginning a day or two before starting the drug and continuing for 2 weeks after stopping the drug (Noyes et al., 1986).
Problems may occur for those prescribed MAO inhibitors and it could decrease the effect of the blood- thinning drug, warfarin.
Studies showed that diets rich in these chemicals, can elevate a person's blood pressure and trigger migraines in patients taking antidepressants known as MAO inhibitors.
Patients taking MAO inhibitors, another kind of antidepressant, should not take EFFEXOR XR.
For the small number of people for whom MAO inhibitors are the best treatment, it is necessary to avoid certain foods that contain high levels of tyramine, such as many cheeses, wines, and pickles, as well as medications such as decongestants.
But when this important conversion is blocked by MAO inhibitors, tyramine builds up, causing the release of norepinephrine.
Fluoxetine is specifically containdicated in combination with MAO inhibitors. Very serious, sometimes fatal, reactions have been reported in patients receiving MAO inhibitors in combination with fluoxetine.
If you eat any of these foods while taking MAO inhibitors, your blood pressure could sky-rocket, creating the risk of a stroke or even death.