ATR

(redirected from MEC1)
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ATR

References in periodicals archive ?
Aconserved polϵ binding module in ctf18-RFC is required for S-phase checkpoint activation downstream of mec1. Nucleic Acids Res 2015;43:8830-8.
In case of mutant strain sml1/mec1 deficient in MEC1, a significant increase in radiation sensitivity was observed.
At the lowest level, experiencing his utter defeat, his feeble yet functional metacognitive executive control (MEC1 depicted in Figure 1) prompted a sort of mindful detachment, fostering his self-scrutiny and assessment.
Muzi-Falconi, "Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1," DNA Repair, vol.
It was previously reported that pathologic changes in hematological malignancies are correlated with the protein profiles of cells; 247 different protein spots were identified between the HL-60 (acute promyelocytic leukemia), MEC1 (B-cell chronic lymphocytic leukemia), CCRF-CEM (T-cell acute lymphoblastic leukemia), and Raji (B-cell Burkitt's lymphoma) cells (102).
Researchers from Cornell University's Weill Institute for Cell and Molecular Biology said that protein Mec1 plays the role of "guardian of the genome," explained Marcus Smolka, assistant professor of molecular biology and genetics.
Resistance to beta-lactams is located on the staphylococcal cassette chromosome (SCCmec), a mobile genetic element, and is encoded by a gene known as mecA, which is regulated by two other genes called mec1 and mecR1.