matrix metalloproteinase

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matrix metalloproteinase

[¦mā·triks mə‚tal·ō′prō·tē·ə‚nās]
(biochemistry)
Any member of a family of at least 19 structurally related zinc-dependent neutral endopeptidases collectively capable of degrading essentially all components of extracellular matrix.
References in periodicals archive ?
MMP Type###OSCC Group Median(IQR)###Control Group Median(IQR)###P valuea
It is known that MMPs are crucial mediators and participators in tumorigenesis and metastasis of cancer (13-15).
Level of MMP-2 and MMP-9 activities in follicular fluid and seminal plasma of infertile couples (n=74) MMP-2 activity (AU) MMP-2 activity (AU) (Equal volume) (Equal protein) Follicular fluid 68.38[+ or -]1.64 67.60[+ or -]1.66 Seminal plasma 45.03[+ or -]1.12 42.81[+ or -]1.28 MMP-9 activity (AU) MMP-9 activity (AU) (Equal volume) (Equal protein) Follicular fluid 94.94[+ or -]1.48 86.03[+ or -]1.80 Seminal plasma 61.98[+ or -]1.25 62.45[+ or -]1.37 AU is an arbitrary unit that is achieved by dividing the number of pixels of MMP band curved to number of pixel of MMP standard curve Table 2.
Norman Lloyd offices at Newtown, Welshpool and Llanidloes will transfer to the existing MMP offices in these three towns.
Currently, there is no consensus method for the measurement of MMP activity in wound fluid.
To investigate whether PAR1 plays a role in IL-1[beta]-induced MMP-1 expression in mesenchymal stem cells, PAR1 Western blotting analysis was performed in cultures pretreated with MMP inhibitors TIMP1 and TIMP2, MMP-1 inhibitor GM6001 (Figure 4(a)), and IL1RA (Figure 4(b)).
Simulating slime-tube experiment utilizing numerical simulation method can predict the MMP value.
In this context, this minireview aimed at identifying studies that correlated circulating MMPs and TIMPs with PCa, focusing on reports that aimed at having them tested as serum/plasma biomarkers and describing accuracy scores, when available.
The suitability of using blood concentration determination various MMPs as prognostic factors was analyzed.
Reduced matrix metalloproteinases (MMPs) activity is accompanied with extracellular matrix (ECM) accumulation in large arteries, leading to the hypertensive arterial remodeling in resistance arteries.
Reports showed that the inhibition of MAPK pathways is closely related to downregulation of MMP secretion [20, 21].
Geyer, "MMP expression in leaking filtering blebs and tears after glaucoma filtering surgery," Graefes Archive for Clinical and Experimental Ophthalmology, vol.