Porphyrins are usually subdivided into classical (with moderate distortion of the planarity of the macrocycle
and well-known properties), and nonclassical (with nontraditional structures and properties) .
As it is well known, porphyrin macrocycles
are tetradentate agents which form complexes with practically all metallic elements of the periodic table [2-4].
However, solvent systems which exhibit preferential solvation could be used to model the inner-sphere solvent structures around the porphyrin macrocycle
The virtual design based research study may be structured in a set of systematic steps that can be followed during each microcycle as well as the macrocycle
. Continuing with the example of the multimedia enhanced online course these steps are conceptualized as follows.
Complex mechatronic product design cycles (macrocycles
) are described in greater detail in .
Within them are approximately one-month chunks known as macrocycles
. Each macrocycle
is composed of weeklong microcycles.
The drug is "the first in a new class of antibiotics called macrocycles
, which inhibit the bacterial enzyme RNA polymerase, resulting in the death of C.
Twenty-four international academics and researchers contribute ten chapters describing state-of-the-art work in the synthesis of macrocycles
for use in supramolecular chemistry, featuring coverage of all major classes of supramolecular compounds.
Gou, Chiral 27-Membered [3+3] Schiff-Base Macrocycles
and Their Reactivity with First-Row Transition Metal Ions, Polyhedron., 27, 1079 (2008).
• Hit ID -encoded libraries, fragments, PROTACs, macrocycles