macropinocytosis


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macropinocytosis

[‚mak·rō‚pin·ə‚sī′tō·səs]
(cell and molecular biology)
A mechanism of endocytosis in which large droplets of fluid are trapped underneath extensions (ruffles) of the cell surface.
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References in periodicals archive ?
Exosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 delivery.
Urinary Extracellular Vesicle: A Potential Source of Early Diagnostic and Therapeutic Biomarker in Diabetic Kidney Disease
The first mechanism is through uptaking the protein from dying neuron through macropinocytosis. The second mechanism is through uptaking the protein through exosomes of neighboring cells.
Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives
Hoffmann et al., "C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells," Journal of Experimental Medicine, vol.
Preconditioning by Hydrogen Peroxide Enhances Multiple Properties of Human Decidua Basalts Mesenchymal Stem/Multipotent Stromal Cells
During viral entry, the MLD and glycan cap facilitate viral adhesion to host cells, leading to macropinocytosis [55, 56].
Investigation of Outbreak-Specific Nonsynonymous Mutations on Ebolavirus GP in the Context of Known Immune Reactivity
The formation of actin filaments manifests in visible cup-shaped ruffles (waves) on the surface and throughout the cell, a behavior that is also known as macropinocytosis, whereby cells produce vesicles that are absorbed into the cell.
Israel : Ben-Gurion University and Weizmann Researchers Shed New Light on Wave Motion on Cellular Membranes that Could Have Implications for Cancer Detection and Treatment
Among the possible mechanisms of uptake, macropinocytosis has also been explored [189].
The Contribution of [alpha]-Synuclein Spreading to Parkinson's Disease Synaptopathy
Swanson, "A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis in macrophages," Journal of Cell Biology, vol.
Short-Term Regulation of Fc[gamma]R-Mediated Phagocytosis by TLRs in Macrophages: Participation of 5-Lipoxygenase Products
There is also an evidence to show that microglia participates in the elimination of fibrillar A[beta] through macropinocytosis [73].
Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms
(2) A review of the receptors involved in macropinocytosis of Flaviviridae [62] was used.
New Targets for Zika Virus Determined by Human-Viral Interactomic: A Bioinformatics Approach
Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake.
IS ONCOLYTIC VIROTHERAPY A VIABLE PLATFORM FOR GLIOMA TREATMENT?
Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells.
Erythrophagocytosis of lead-exposed erythrocytes by renal tubular cells: possible role in lead-induced nephrotoxicity
Parker, "The mechanism of cell uptake for luminescent lanthanide optical probes: the role of macropinocytosis and the effect of enhanced membrane permeability on compartmentalisation," Organic and Biomolecular Chemistry, vol.
Macrocyclic assembly: a dive into the pecking order and applied aspects of multitalented metallomacrocycles

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