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A tumor characterized by the diffuse proliferation of peripheral nerve elements. Also known as endoneural fibroma; myxofibroma of nerve sheath; neurofibromyxoma; perineural fibroblastoma; perineural fibroma.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a benign tumor that originates in membranes of peripheral nerves and is localized in any part of the body along the path of a nerve trunk. Neurofibromas most often affect the sciatic and intercostal nerves. The multiple occurrence of neurofibromas is called neurofibromatosis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Van Der Putten, "Upper gastrointestinal bleeding due to a malignant Schwannoma of the stomach," European Journal of Gastroenterology and Hepatology, vol.
Generally gastric malignant schwannomas can be distinguished from benign schwannomas on the basis of histological and immunohistochemical features, not by clinical symptoms or imaging studies.
Malignant peripheral nervesheath tumors (malignant schwannomas).
The overall incidence of malignant schwannomas was 0.5% (range, 0-2.0%) in males and 0.1% (range, 0-1.0%) in females.
Malignant peripheral nerve sheath tumors (malignant schwannomas) in children.
The term epithelioid malignant schwannoma has been applied to cases in which aggressive tumors are derived from nerve sheaths and contain tumor cells having visible cell borders, epithelial-type nests, and immunoreactivity for S100 protein, but not for keratin.
XII: Schwann cell tumors (Neurilemoma, Neurofibroma, Malignant schwannoma).
Malignant peripheral nerve sheath tumor--also known as neurogenic sarcoma, malignant neurilemoma, malignant schwannoma, and neurofibrosarcoma--is an uncommon neoplasm that originates in Schwann's cells of the nerve sheath.
Depending on the patient's age and the location of the tumor, the differential diagnosis includes malignant schwannoma, malignant fibrous histiocytoma, fibrosarcoma, amelanotic melanoma, malignant lymphoma, squamous cell carcinoma, extramedullary plasmacytoma, metastatic tumor, glandular tumor, chondroma, chondrosarcoma, osteogenic sarcoma, and inverted papilloma.
Malignant schwannoma is an aggressive tumor that carries a poor prognosis despite wide excision, chemotherapy, and radiotherapy.
On macroscopic examination, the cut surface was grayish-white and exhibited focal myxoid areas, The lesion was diagnosed as a malignant schwannoma. The patient was discharged and kept under surveillance without any adjuvant therapy.

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