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Extremely high fever.



elevation of the body temperature in humans and animals caused by a disturbance in heat loss. A fever of 42°C is considered critical: lethal changes in the brain tissue develop. The critical temperature for an individual may range from 40° to 44°C. A few cases have been recorded in which persons with a temperature of 44°C have recovered. Moderate hyperpyrexia may be induced artificially for therapeutic purposes (treatment of syphilis and other diseases). Artificially induced hyperpyrexia is called hyperthermia.


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Mnogotomnoe rukovodstvo po patologicheskoi fiziologii, vol. 2. Moscow [1966].
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