malignant

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malignant

1. Pathol (of a tumour) uncontrollable or resistant to therapy; rapidly spreading
2. History (in the English Civil War) a Parliamentarian term for a royalist

malignant

[mə′līg·nənt]
(cell and molecular biology)
Pertaining to cells that have undergone phenotypic transformation by oncogenes or protooncogenes.
(medicine)
Endangering the life or health of an individual.
Of or pertaining to the growth and proliferation of certain neoplasms which terminate in death if not checked by treatment.
References in classic literature ?
returned the savage, with a malignant laugh: "why should Le Renard go among the muskets of his warriors, when he holds the spirit of the gray-head in his hand?
To him the police were always actuated by malignant impulses and the rest of the world was composed, for the most part, of despicable creatures who were all trying to take advantage of him and with whom, in defense, he was obliged to quarrel on all possible occasions.
But more frightful even, and more heart-strangling was it, when it again became silent and still all around, and I alone sat in that malignant silence.
Often it was only the smallest trace, Watson, the faintest indication, and yet it was enough to tell me that the great malignant brain was there, as the gentlest tremors of the edges of the web remind one of the foul spider which lurks in the centre.