Mandelic Acid


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mandelic acid

[man′del·ik ′as·əd]
(organic chemistry)
C6H5CHOHCOOH A white, crystalline compound, melting at 117-119°C, darkening upon exposure to light; used in organic synthesis.

Mandelic Acid

 

amygdalic acid, phenylglycolic acid; the simplest aliphatic-aromatic hydroxy acid.

Mandelic acid exists in two optically active forms, ( + ) and ( − ), as well as in the racemic (paramandelic) ( ± ) form. The first two types melt at 133.3°C; the racemic form

melts at 120.5°C. Natural ( − )-mandelic acid occurs in the bitter almond as the glycoside amygdalin, from which it can be extracted by hydrolysis; ( + )-mandelic acid is present (in a bound form) in the fruits and flowers of the common elder; and (±)-mandelic acid is obtained from benzaldehyde:

References in periodicals archive ?
Group I: topical 4% hydroquinone and group II: topical 4% hydroquinone and 10% mandelic acid serum.
1995 Mandelic acid img/g creatinine) 58 De Rosa et al.
Finally, the extraction time of 60 minutes was chosen due to the 100% enrichment of the external and internal standards, mandelic acid (MA, ISX) and TCA ([IS.sub.2]).
We assessed the exposure by measuring the concentrations of styrene in air and in blood and of mandelic acid, phenylglyoxylic acid, 4-vinyl phenol conjugates and regioisomefic phenyl hydroxyethyl mercapturic acids in urine.
Meanwhile, Taiwan's leading derm brand Dr.Wu provides Chinese consumers with a skin assessment before recommending suitable products like its Daily Renewal Serum, which is formulated with macromolecule mandelic acid. The ingredient is said to gently, yet quickly, remove aged skin layers.
* Very superficial chemical peels with salicylic acid alone, or in combination with mandelic acid, may improve outcome faster and decrease PIH that already exists.
New Brightening Cleanser and Brightening Toner formulations recently launched by Le Mieux Cosmetics, Los Angeles, tout mandelic acid and glutathione in addition to licorice root, bearberry and papaya extracts.
* McKinley Skincare - Product line composed of active ingredients with clinical claim substantiation for anti-aging (Beta-Glucan M[TM], Capryloyl Salicylic Acid, Nuovo-Proline16[R], NuovoSoft-16[R]), anti-oxidant (Ferulic Acid), anti-acne (Mandelic Acid), and skin lightening (G-Hexuron[R], LHexuron[R], SkinBrite-30[R]) applications.