Table 9 Sensitivity, specificity, accuracy, positive and negative predictive values of the Mantoux
test results, microscopy using Ziehl-Neelsen stain, microbiological culture using Lowenstein-Jensen medium and PCR for cutaneous tuberculosis (N=30).
While investigating for probable clues to suggest TB, it has been evident that in some patients, the Mantoux
test and CSF TB-PCR can become negative.
Latent or active tuberculosis was evaluated by means of the Mantoux
skin test (233 patients) and/or QuantiFERON-TB Gold (97 patients) (in 15 patients both, the Mantoux
skin test and QuantiFERON-TB Gold were carried out).
(10,11) Most reported MAC-infected patients had a positive Mantoux
test and persistent pyuria.
However, since the pathological analysis revealed no acid fast bacilli a Mantoux
assay was requested in addition to bronchoalveolar lavage in order to confirm the TB suspicion.
ID adapters offer an easy-to-use, low-cost aid for ID injections using Mantoux
technique and currently available needles and syringes (3).
test demonstrated an induration of 28 mm at the end of 72 hours (N < 10 mm).
Unfortunately, the current method of ID delivery, the Mantoux
technique, can be difficult to master.
Skin Test is not a confirmatory test for active TB disease.
The product is also more accurate and easier-to-handle in comparison to the tuberculin skin test (TST or Mantoux
Serum ceruloplasmin level was within normal limit (35.68 U/L) and Mantoux
test was negative.
According to the company, the ID adapter will complement its portfolio of prefilled syringe offerings and technologies, conserve the supply of high-value vaccines, provide patients significant benefit through more reliable injection and will provide an alternative to the Mantoux
method, the industry standard for intradermal injection since 1907.