Marshall Warren Nirenberg

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Nirenberg, Marshall Warren


Born Apr. 10, 1927, in New York City. American biochemist. Member of the US National Academy of Sciences (1967) and the American Academy of Arts and Sciences (1966).

Nirenberg received the M.S. degree from Florida State University in 1952, and then worked at the University of Michigan from 1952 to 1957. In 1957 he began working at the Institute of Arthritis, Metabolism, and Digestive Diseases. Since 1962 he has headed the biochemical genetics laboratory at the National Heart and Lung Institute.

Nirenberg’s main works are concerned with the interpretation of the genetic code. He demonstrated that polyuridylic acid serves as the matrix for polyphenylalanine synthesis and that the UUU (uracil-uracil-uracil) codon determines the inclusion of phenylalanine in the polypeptide chain during protein synthesis. Nirenberg, together with R. Holley and H. G. Khorana, was awarded a Nobel Prize in 1968.


In Russian translation:
“Geneticheskii kod (II).” In the collection Struktura i funktsiia kletki. Moscow, 1964.
References in periodicals archive ?
In support of the existence and usefulness of method B, Bonner (2005) cited the Nobel Prizewinning research that Marshall Nirenberg conducted in the early 1960s.
In the end, the code was cracked in the government-issue National Institutes of Health laboratory of Marshall Nirenberg and Heinrich Matthaei in 1961.
One recent commentator notes that the antic coding of the 1950's provided Marshall Nirenberg with the conceptual apparatus necessary to grasp the problem he was laboring to solve.
Lewis, California Institute of Technology, 1995-Physiology or Medicine; William Lipscomb, Harvard University, 1976-Chemistry; Ferid Murad, University of Texas at Houston, 1998-Physiology or Medicine; Marshall Nirenberg, National Institutes of Health, 1968-Physiology or Medicine; Sir Paul Nurse, Cancer Research UK, 2001-Physiology or Medicine; Burton Richter, Stanford Linear Accelerator Center, 1976-Physics; Richard J.
Marshall Nirenberg and Heinrich Matthaei of the National Heart Institute, now the NHLBI, broke the genetic code and showed how the messages of heredity were spelled out and could be translated.
Marshall Nirenberg, 1968 Nobel laureate in Medicine from the National Institutes of Health, will be honored with "Life-Time Achievement Awards.
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