Given individual genetics and chemistry, and the fact that mast cells
can produce over 200 different biochemical mediators depending on the stimulus they are exposed to, there are an astonishing number of symptoms that mast cell
activation can produce.
of mast cells
in ENL was less than the non-reactional group.
The study increases understanding of how mast cells
are formed and could be important in the development of new therapies, for example for mastocytosis for which treatment with imatinib/Glivec is not effective.
Spleen mast cells
purified by flow cytometry sorting were plated on 24-well chamber slides and fixed with paraformaldehyde for 30 min.
Mastocytosis represents a spectrum of clinical disorders with a common phenotype of tissue mast cell
Prevalence and importance of internal tandem duplications in exons 11 and 12 of c-kit in mast cell
tumors of dogs.
Education related with use of epinephrine autoinjector in case of sudden hypotension which is observed as a result of acute degranulation of mast cells
should be given.
Characteristics of Bone Marrow Mast Cells
and Their Exosomes.
11 In Toluidine Blue-stained sections, the most intense areas of mast cells
were examined under HPF, and under 10HPFtotal number of mast cells
at lamina propria was recorded.
The number of mast cells
that was present in 10 consecutive high-power fields (hotspots) was counted in all sections.
Histamine released by degranulation of mast cells
can also be measured within 5-10 minutes, but remains elevated for only 30-60 minutes and therefore has very limited value.
It is also proposed that nitric oxide synthase may also protect mast cells
from activation induced cell death.