fixation

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fixation:

see psychoanalysispsychoanalysis,
name given by Sigmund Freud to a system of interpretation and therapeutic treatment of psychological disorders. Psychoanalysis began after Freud studied (1885–86) with the French neurologist J. M.
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.

Fixation

 

a method of preserving the structure of animal and plant cells and tissues through treatment with chemical and physical agents. Fixation is used to obtain medicinal preparations.

Physical techniques include drying and freezing at low temperatures in a vacuum (lyophilization). Specimens may be treated chemically with such reagents as formaldehyde, alcohol, acetone, and osmium tetroxide. Many reagents are used in combination with other substances, such as potassium bichromate, mercuric chloride, and picric acid; such fixatives are usually named after the researchers who proposed them, for example, Zenker’s and Maximow’s fixatives and Flemming’s, Carnoy’s, and Bouin’s solutions. The choice of technique depends on the properties and size of the specimen and the purpose of the study. For example, alcohol fixation is adequate to preserve nucleic acids, but enzyme activity is completely preserved only after lyophilization. Fixation in aldehydes is recommended for electron microscopy. Double fixation is used for better preservation of tissue, that is, primary fixation with an aldehyde fixative and a second fixation with osmium tetroxide.

REFERENCES

Roskin, G. I., and L. B. Levinson. Mikroskopicheskaia tekhnika, 3rd ed. Moscow, 1957.
Rukovodstvo po tsitologii, vol. 1. Moscow-Leningrad, 1965.

M. E. ASPIZ

fixation

[fik′sā·shən]
(psychology)
A rigid habit developed as a consequence of repeated reinforcement, or of frustration.

fixation

1. Psychol
a. the act of fixating
b. (in psychoanalytical schools) a strong attachment of a person to another person or an object in early life
2. Chem
a. the conversion of nitrogen in the air into a compound, esp a fertilizer
b. the conversion of a free element into one of its compounds
3. the reduction of a substance from a volatile or fluid form to a nonvolatile or solid form
References in periodicals archive ?
The rationale of this study is to observe weight loss in patients undergoing maxillomandibular fixation due to trauma.
"Transoral 2.0-mm locking miniplate fixation of mandibular fractures plus 1 week of maxillomandibular fixation: a prospective study." Journal of oral and maxillofacial surgery 63(12): 1737-41.
For most of the fractures open reduction and internal fixation were used which included titanium mini plates recon- struction plates resorbable miniplates with or without Maxillomandibular fixation (MMF).
Unilateral fracture of the condyle age above 12 years irrespective of sex medically fit to undergo sur- gical intervention sufficient bilateral dentition to allow maxillomandibular fixation on assessment of occlussal relationship and patient's consent to participate and gross pre-traumatic skeletal mal-relationship of the jaws.