Johann Friedrich Meckel

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Meckel, Johann Friedrich

 

Born Oct. 17, 1781, in Halle, Saxony; died there Oct. 31, 1833. German biologist.

Meckel studied in Halle, Göttingen, Würzburg, and Vienna. In 1808 he became a professor at Halle. His principal works deal with comparative vertebrate morphology. Meckel was one of the creators of the theory that individual development in extant higher animals passes through stages similar to the adult states of extant lower animals. Meckel described a number of morphological formations, which are named for him. In 1812 he translated into German K. F. Wolffs On the Formation of the Intestinal Tract in the Chick (1768), which advanced the dissemination of his theory of epigenesis.

WORKS

Beiträge zur vergleichenden Anatomic, 2 vols. Leipzig, 1811.
System der vergleichenden Anatomie, 5 vols. Halle, 1821–33.
References in periodicals archive ?
A distinctive triad of malformations of the central nervous system in the Meckel-Gruber syndrome.
First-trimester diagnosis of Meckel-Gruber syndrome by transabdominal sonography in a low-risk case.
Dr Colin A Johnson, who led the research, said: "Identifying mutations in this gene that are responsible for Meckel-Gruber syndrome should make screening for this devastating genetic condition far easier.
The differential diagnosis ACS includes Greig's Cephalopolysyndactyly syndrome, Oro-facial digital syndromes Type I and II, Meckel-Gruber syndrome, Smith-Lemlioptiz syndrome, RubinsteinTaybi syndrome.
Table: Associated Findings in DW Syndrome: cNS Findings Non CNS findings Dysgenesis of corpus callosum Orofacial deformities Lipoma of corpus callosum cleft palate Holoprosencephaly polydactyly Porencephaly Syndactyly Dysplasia of cingulate gyrus Cardiac anomalies Schizencephaly Urinary tract anomalies (polycystic kidneys) polymicrogyria Cataract Cerebellar heterotopia Retinal dysgenesis Occipital encephalocoele Choroid coloboma Microcephaly Facial haemagioma Dermoid cysts Hypertelorism Malformation of cerebellar Meckel-Gruber syndrome folia; inferior olivary nucleus Hamartoma of tuber cinereum Neurocutaneous melanosis Syringomyelia Klippel-Feil deformity Spina bifida Lumbosacral meningocoeles Spinal Lipoma
The first reports of Meckel-Gruber syndrome were published in 1822 by Johann Friedrich Meckel.