RET fusions are implicated in several cancers including non-small cell lung cancer, papillary thyroid cancer and medullary thyroid cancer
This clinical trial of of BLU-667 is a part of the partnership's ongoing, global Phase I ARROW trial that is designed to evaluate its overall response rate (ORR), duration of response, pharmacokinetics, pharmacodynamics and safety in patients with RET-altered non-small cell lung cancer (NSCLC), medullary thyroid cancer
(MTC) and other advanced solid tumors.
One author was a member of the Data Monitoring Committee of the Medullary Thyroid Cancer
Consortium Registry, which is supported by pharmaceutical companies.
Researchers used the Afirma XA to conduct RNA sequencing on 90 thyroid fine needle aspiration samples that had been diagnosed with medullary thyroid cancer
through the Afirma GSC.
Caprelsa, for the treatment of medullary thyroid cancer
The diagnosis revealed a thyroid mass present in his body and experts suggested total thyroidectomy with modified radical neck dissection for the medullary thyroid cancer
. Upon surgery, it was determined that the mass was extremely rigid and infiltrating important vessels and the trachea.
A genomic alternative to identify medullary thyroid cancer
preoperatively in thyroid nodules with indeterminate cytology.
If you have a family history of thyroid cancer a blood test can reveal a genetic mutation for familial medullary thyroid cancer
. This type of cancer is usually treated and prevented by removing the entire gland.
 2/14 (14.3%) Present study 2/3 (66.7%) DTC: differentiated thyroid cancer; PTC: papillary thyroid cancer; FTC: follicular thyroid cancer; MTC: medullary thyroid cancer
; NA: not available.
Blueprint Medicines is advancing four programs in clinical development for subsets of patients with gastrointestinal stromal tumors, hepatocellular carcinoma, systemic mastocytosis, non-small cell lung cancer, medullary thyroid cancer
and other advanced solid tumors, as well as multiple programs in research and preclinical development.
Human calcitonin (CT)11 is a tumor marker essential for diagnosis and follow-up of medullary thyroid cancer
(MTC) (1-4); high basal serum CT concentrations are noted in sporadic and familial MTC.
Here, we present a family in which MEN2A was detected in the index case and two brothers had detected pheochromocytoma and medullary thyroid cancer