Within the cytoplasm is a schizont containing numerous round cross-sectioned (arrowhead) and longitudinally sectioned (arrows) merozoites
(bar = 5 Hm).
The compartmental model assumes seven interacting populations of sporozoites S(t), susceptible hepatocytes H(t), infected hepatocytes [H.sub.X](t), susceptible red blood cells (RBCs) R(t), infected red blood cells (IRBCs) [R.sub.X](t), merozoites
M(t), and macrophages Z(t) at any time t.
The success of evasion depends on merozoites
and infected red blood cell (iRBC) surface proteins.
AMA-1 is considered plausible vaccine candidate antigen, as studies show it to be conserved, with limited polymorphism reported when compared with other merozoite
antigens (Remarque et al., 2008).
Xue, A Novel Serine/Threonine Protein Phosphatase Type 5 from Second-Generation Merozoite
of Eimeria tenella is Associated with Diclazuril-Induced Apoptosis, Parasitol.
surface proteins in red blood cell invasion, immunity and vaccines against malaria.
into erythrocyte begins with an initial weak attachment of the merozoite
to the red blood cell (RBC) surface through yet-unidentified parasite receptor-RBC interaction, followed by a reorientation that ultimately brings the apical end of the merozoite
into close apposition with the RBC surface (4,5).
falciparum is evenly expressed in asexual blood-stage parasites during development from merozoites
via trophozoites to schizonts, as well as in the sexual gametocyte forms.
After infection in humans, the parasite (known as sporozites) travel through the bloodstream to the liver, where they mature and release another parasite - merozoites
. These enter the bloodstream and infect the red blood cells and cause fever, chills, nausea, headache and sweating.
Due to the high density of peripheral schizonts, the smear was re-examined by the expert microscopist who confirmed the same diagnosis but were cautious about the morphology of the schizonts, specifically their pigmentation and the number of merozoites
. Molecular diagnosis was carried out by nested polymerase chain reaction (PCR) with primers described by Snounou et al (3) and modified cycling parameters as described by Johnston et al (4) which detected coinfection with P.
After staining with both SYBR Green I and CD235A, few signals were found from the right lower quadrant (Figure 2(e)), which suspected the presence of merozoites
in Figure 1.
Examination of Giemsa-stained thin blood smear revealed the presence of typical large merozoites
and trophozoites of B.